1440 / 1816
Conundrum of PST: discussion & conclusions
•
Primary systemic treatment is increasingly used
•
Radiation therapy is indicated for most patients
•
The role of surgery is questioned
•
High-level evidence is missing
•
Available evidence supports basing indications for RT on
disease extent at diagnosis
•
Individualisation based on tumour- and patient-related
factors can be done, combined with the response to PST
•
For fine-tuning we need results from on-
going and future clinical trials