Introduction
•
Primary systemic treatment (PST) is being given more frequently
•
Timing of systemic treatment: not relevant for outcome,
as long as
treatment consists of same ingredients (?)
•
Indications for locoregional RT: based upon pathologic findings after
primary surgery
how to interpret ypTNM status ?
Central question:
Can subgroups be identified in whom locoregional treatment after PST
can be reduced ?




