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Omission of breast surgery after PST
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Eliminating Breast Cancer Surgery in Exceptional Responders With PST
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Study from MD Anderson NCT02945579, phase 2 study
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If c/pCR based on image guided breast biopsy: Only RT breast < 12
weeks of end of chemotherapy
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Inclusion 2017 – 2022, aimed to include 50 patients
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Primary endpoint: Feasibility i.e. no IBTR < 6 months for first 6 patients;
then: 5 yr IBTR