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Omission of RT thoracic wall

SUPREMO study (NCT00966888)

www.supremo-trial.com

Selective Use of Postoperative RadiothErapy after MastectOmy

Worldwide study of the NHS- UK:

Patients with (y)pT1-2N1 disease; (y)pT1-2N0 with G3 and / or LVI

Randomised between

thoracic wall RT or no thoracic wall RT

Patients treated with PST were eligible as well

Target was 1600 patients; trial closed April 30th 2013, 1688 patients

enrolled

Data are maturing…

Major contributors: UK (75%), NL (10%)