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Tamoxifen (5y) vs no Tamoxifen

Endometrial cancer

Relative risk: 2.40 ( p<0.00002)

Thrombo-embolic disease/Vascular mortality

Little net effect on overall vascular mortality

Relative risk trombo-embolic disease: 2.50 (p: 0.07)

Overall, the absolute risk of death for both endometrial cancer and

vascular complications is 0.2% in ten years ( ECCTCG 2005)

EBCTCG, Lancet 2005

EBCTCG, Lancet 2011