Tamoxifen (5y) vs no Tamoxifen
Endometrial cancer
Relative risk: 2.40 ( p<0.00002)
Thrombo-embolic disease/Vascular mortality
Little net effect on overall vascular mortality
Relative risk trombo-embolic disease: 2.50 (p: 0.07)
Overall, the absolute risk of death for both endometrial cancer and
vascular complications is 0.2% in ten years ( ECCTCG 2005)
EBCTCG, Lancet 2005
EBCTCG, Lancet 2011