Quantitative Methods 2017

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Laterality and mean heart dose in case-control

study of MCEs after breast cancer RT

Left-sided breast cancer:

Cases: 56%, controls: 50%

p<0.001

Mean dose to heart:

• Cases: 5.4 Gy, controls: 4.5 Gy

• p<0.001

NEJM 2013; 368:987-98