1218-1219 / 1676
FMB
Rate
ratio*
2p
Cancer treatments
Type of surgery
Mastectomy
1.0†
0.2
Breast-conserving
0.9
Adj hormonal therapy No
1.0
0.1
Yes
1.2
Adj chemotherapy
No
1.0
0.1
Yes
0.7
Ovarian ablation
No
1.0
0.5
Yes
0.9
Tumour characteristics
Nodal status
Negative
1.0
0.06
Positive
1.2
Tumour size
< 2 cm
1.0
1.0
2-5 cm
1.0
Tumour location
Outer quadrants
1.0
0.2
Inner quadrants
0.8
*Estimated by logistic regression after stratification for country, age at cancer diagnosis, year of cancer
diagnosis, and years from cancer diagnosis to first subsequent MCE (cases) or index date (controls)
† Category listed first is baseline
NEJM 2013; 368:987-98
Association between tumour characteristics, cancer treatments,
and subsequent rate of MCEs in women irradiated for breast cancer