1226-1227 / 1676
FMB
Rate ratio*
2p
History of ischemic heart
disease (IHD)
No
1.0†
0.00004
Yes
6.7
Circulatory disease
other than IHD
disease
No
1.0
0.0003
Yes
1.5
History of diabetes
No
1.0
<0.00001
Yes
3.2
History of COPD
No
1.0
0.00007
Yes
6.3
Current smoker
No
1.0
0.00002
Yes
1.9
Body mass index (kg/m
2
) <30
1.0
0.002
30+
1.6
Analgesic medication
No
1.0
0.02
Yes
1.6
*Estimated by logistic regression after stratification for country, age at cancer diagnosis,
year of cancer diagnosis, and years from cancer diagnosis to first subsequent MCE (cases)
or index date (controls)
† Category listed first is baseline
NEJM 2013; 368:987-98
Association between cardiac risk factors and subsequent rate of major
coronary events in women irradiated for breast cancer