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NTCP SW-IMRT (%)

NTCP Standard IMRT (%)

Christianen, et al. in press Radiother Oncol

Step 4: Clinical validation study

ΔNTCP plot (n=186)

HIGH

reduction

ΔNTCP >5%:

46%

LOW

reduction

ΔNTCP 0-5%:

54%

Nothing

to spare

Overlap with

target volume

ΔNTCP: 5%

Redistribution

problem