0
10
20
30
40
50
60
70
0
10
20
30
40
50
60
70
NTCP SW-IMRT (%)
NTCP Standard IMRT (%)
Christianen, et al. in press Radiother Oncol
Step 4: Clinical validation study
ΔNTCP plot (n=186)
HIGH
reduction
ΔNTCP >5%:
46%
LOW
reduction
ΔNTCP 0-5%:
54%
Nothing
to spare
Overlap with
target volume
ΔNTCP: 5%
Redistribution
problem