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Example
•
‘Fit’ a step function to the following data
•
What is L for a step function with D
50
=21 Gy?
•
What is L for a step function with D
50
=25 Gy?
Patient
Dose
Toxicity?
1
10 Gy
Yes
2
20 Gy
No
3
22 Gy
No
4
28 Gy
Yes
5
30 Gy
Yes
Tox i
tox
Tox
i
tox
D p
Dp
L
) (
1
) (
50
50
What would your best bet on D
50
be from intuition?