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Example

‘Fit’ a step function to the following data

What is L for a step function with D

50

=21 Gy?

What is L for a step function with D

50

=25 Gy?

Patient

Dose

Toxicity?

1

10 Gy

Yes

2

20 Gy

No

3

22 Gy

No

4

28 Gy

Yes

5

30 Gy

Yes

Tox i

tox

Tox

i

tox

D p

Dp

L

) (

1

) (

50

50