227 / 1498
Second malignancy
No. of
pts
5-yr survival
estimate (%)
95% CI
Median survival,
yrs
All sites
181
38.1
(29.7-46.5)
3.2
Acute leukemia
23
4.9
(0.0-14.2)
0.4
NHL
24
49.6
(28.0, 71.2)
2.4
All solid tumors
131
42.1
(31.6, 52.5)
4.3
Breast
39
76.1
(57.4-94.8)
Not yet reached
Lung
22
0.0
—
1.0
Gastrointestinal
24
12.4
(0-28.1)
1.9
Ng et al., Blood 2002
Survival outcome after a second malignancy
n=1319 ; treatment period: 1969 and 1997; median fup 12 years.