383 / 1708
SIOP/UKCCSG (PNET-3)
•
217 pts with M0 or M1
disease randomized to
35 Gy CSRT, 55 Gy
PFRT +/- pre-RT
VCR, VP-16,
Carboplatin and CPM
•
Improvement in 5-
year event-free
survival with
chemotherapy (74.2%
vs. 59.8%, p = 0.036)
Taylor RE et al. J Clin Oncol 2001