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CCG/RTOG

233 pts randomized to 35-40 Gy CSRT, 50-55 Gy PFRT +/-

VCR, CCNU, prednisone x 1 year

No difference in survival

Benefit in those receiving chemotherapy with T3, T4 or M+

disease

Evans AE et al. J Neurosurg 1990; 72:572-82