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POG

78 pts randomized to 35 Gy CSRT + 54 Gy PFRT +/-

MOPP

Borderline difference in 5-year survival, favoring

chemotherapy, 74% vs. 56%, (p = 0.06)

Pts > 5 yrs old, females and non-whites had the most

benefit

Krischer JP et al. J Neurosurg 1991; 74:905-9