377 / 1708
Craniospinal RT Dose (1800 cGy)
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Indiana University
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7 children (age 20-64 mos) treated with 4 mos of
chemotherapy followed by 1800 cGy CSRT + 54 Gy PF boost
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3 patients relapsed (all outside PF)
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2 of 3 were salvaged
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4/6 survivors have endocrine deficits
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All 6 required special assistance in school
Jakacki RI et al. Int J Radiat Oncol Biol Phys 2004; 60:531-6