380 / 1708
SIOP-1
•
286 pts randomized to 30-45 Gy CSRT, 50-55 Gy PFRT
+/- VCR + CCNU x 1 year
•
No difference in survival
•
Benefit in patients receiving chemotherapy in those with
subtotal resection, brainstem involvement and T3 or T4
disease
Tait DM et al. Eur J Cancer 1990; 26:464-9