376 / 1708
Craniospinal RT Dose (1800 cGy)
•
Children’s Hospital of Philadelphia
•
A prospective study used 1800 cGy CSRT and 5580 cGy to the
posterior fossa with 8 cycles of VCR, CCNU and CDDP in 10
children 18-60 mos
•
4-year survival was 69%
•
No marked change in IQ scores among survivors
Goldwein JW et al. Int J Radiat Oncol Biol Phys 1996; 34:899-904