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DVHs are based only on

anatomy

(knowledge and

interpretation) and

dose distribution

reduced to a

2D estimate

Dose-response model based on few geometrical

parameters could

omit clinical conditions

differentiating the patients

When referring

outcome prediction

on parameters

derived from literature try to compare your evaluation

to the

same conditions

used by publications

authors (if available!)

New methods for

patients classification

are

required to achieve a robust and reliable evaluation

Beyond the DVHs