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Reliability of radiobiological evaluation

Solution 2: multivariate regression modeling

J El Naqa et al. Multivariable modeling of radiotherapy outcomes, including dose-volume and

clinical factors. Int J Radiat Oncol Biol Phys. 64, (4), 1275–1286, 2006.

Stim6rel

Age

Gender

Ethnicity

Startdate

Technique

Treat aim

KPS

Chemo

AJCC

Tx duration

Histology

Tum subsite

MdoseExp

Stim6rel

Age

Gender

Ethnicity

Startdate

Technique

Treat aim

KPS

Chemo

AJCC

Tx duration

Histology

Tum subsite

MdoseExp

0

0.5

1.0

Creation of a correlation

matrix to establish the

relationships among

different analyzed factors