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Reliability of radiobiological evaluation
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Possible solutions:
1. “Large database” modeling
2. Use of automatic computer bots
3. Multiparametric modeling
Inferential statistics
Bayesian approach
Use of support-vector-machines
Other…
4. Extension of data-mining in multi-centric perspective
5. Definition of multi-centric “ontology” for data
classification and collection minimizing errors
JO Deasy et al. Improving normal tissue complication probability models: the need to adopt
a “data-pooling” culture. Int J Radiat Onc Biol Phys. 76, (3), S151–S154, 2010
V Valentini, N Dinapoli, A Damiani. The future of predictive models in radiation
oncology: from extensive data mining to reliable modeling of the results. Future Oncol.
(2013) 9(3), 311–313