290 / 435
Dan-Hui Dorothy Yang, Ph.D.
Contact Info:
Email:
dorothy_yang@agilent.com ;Tel: (408) 553 7091 (O); (408) 368 1405 (C)
Objective:
Expert Review Panel for AOAC
Education:
Degree:
University
Year
B.Sc.(Chemistry)
Peking University, P.R. China
1988
Ph.D. (Chemistry)
Universit
é
Libre de Bruxelles, Belgium
1992
Relevant Experience:
Aug. 2000 – Present:
Senior Scientist
,
Agilent Technologies, Inc
.
Mass Spectrometers and Reagent Kits Related Experience: 2006-Present
Food safety and environmental market applications on Agilent triple quadrupole and time
of flight (QTOF) Mass Spectrometry – designed applications tests and executed plan;
conducted internal and external trainings/webinars. Focused on multi-residue pesticides
screening in foods, estrogens analysis in milk, pesticides/pharmaceutical and personal
care product detection in surface water.
Supported sales team on new product launch, customer education and conducted “show
and tell” demos to customers.
Mentored junior team members on application test planning and applied market
application test management.
Validated Agilent reagent kits for food safety market: trouble shooting on veterinary drug
kits, new method development for challenging compounds, and proposing changes for
customers.
Worked with genomic reagent team (former Stratagene) to develop single quadrupole
Mass Spectrometer clinical application using MassCode technology – PCR bioreagent
validation, mass tags selection, assay protocol development and software testing.
Developed an automated HPLC – single quadrupole MS method for PCR amplicon
purification and detection.
Developed methods on blood vitamin D, testosterone, thyroid hormones, dihydroxy
vitamin D testing using low-end and high-end triple quadrupole mass spectrometer.
HDL 2b (High Density Lipoprotein 2b) Development and 510K Filing: 2005 - 2009
Developed HDL subfractionation assay on microfluidic electrophoresis platform –
reagents development including polymer matrix selection for electrophoresis, buffers and
florescent dyes developments.
Set QC specifications for all reagents components and transfer the process to
manufacturer.
Conducted design verification and design validation for both reagents and software.
Supervised multi-sites validation and clinical trials in compliance with quality system
requirement.
Submitted Agilent first IVD 510K to US FDA and was responsible for technical write-
ups.
AOAC OMB Meeting Book
273