119
Biophysical Society 58
th
Annual Meeting, San Francisco, California
T
U
E
S
D
A
Y
2151-P
lat
10:00
am
CELL DIVISIONS CAUSE LONG-RANGE WELL-ORDERED
VORTICITY PATTERNS IN ENDOTHELIAL TISSUE. Ninna S. Rossen,
Jens M. Tarp, Joachim Mathiesen, Mogens H. Jensen,
Lene Oddershede
8:15
am
–10:15
am
, R
oom
132/133
Platform
Intrinsically Disordered Proteins
Co-Chairs
Birthe Kragelund, University of Copenhagen, Denmark
Trevor Creamer, University of Kentucky
2152-P
lat
8:15
am
PREDICTION OF THE EFFECTS OF THE VAL66MET
POLYMORPHISM ON THE CONFORMATIONAL ENSEMBLE OF
AN INTRINSICALLY DISORDERED PROTEIN, BRAIN-DERIVED
NEUROTROPHIC FACTOR.
Ruchi Lohia
, Reza Salari, Grace Brannigan
2153-P
lat
8:30
am
HOW DO INTERACTIONS IN CIS WITH ORDERED DOMAINS
INFLUENCE SEQUENCE-ENSEMBLE RELATIONSHIPS OF
INTRINSICALLY DISORDERED REGIONS?
Anuradha Mittal
,
Kanchan Garai, Rohit V. Pappu
2154-P
lat
8:45
am
THE C-TERMINAL V5 DOMAIN OF PROTEIN KINASE C
α
IS A
MULTI-FUNCTIONAL INTRINSICALLY DISORDERED PROTEIN
MODULE.
Yuan Yang
, Tatyana I. Igumenova
2155-P
lat
9:00
am
C-TERMINAL ERK D- (AND F-LIKE) DOMAINS LINKTHE NA
+
/H
+
EXCHANGER NHE1 TO ERK2 PHOSPHORYLATION AND
REGULATION VIA SCAFFOLDING. Ruth Hendus-Altenberger,
Jeff Schnell, Elena Pedraz, Jonas Marstrand Lacour, Jane Johansen,
Stine F. Pedersen,
Birthe B. Kragelund
2156-P
lat
9:15
am
SPEED DATING WITH KIX: A SINGLE DOMAIN THAT HAS
MANY PARTNERS.
Sarah L. Shammas
, Jane Clarke
2157-P
lat
9:30
am
MOLECULAR SIMULATIONS OF THE DYNAMICS OF
DISORDEREDPROTEINS.
W. Wendell Smith
, Po-Yi Ho,
Elizabeth Rhoades, Corey O’Hern
2158-P
lat
9:45
am
THE PROTECTIONOFMEMBRANES FROMCOLD-STRESS: A
STRUCTURAL STUDYOFTHE INTRINSICALLY DISORDERED
DEHYDRINBOUNDTOMICELLES AND LIPOSOMES.
Steffen P. Graether
, Matthew Clarke, JosephineWarnica, John Atkinson,
Jeffrey Madge
2159-P
lat
10:00
am
TRANSIENT DISORDER: CALCINEURIN AS AN EXAMPLE.
Trevor P. Creamer
, Tori B. Dunlap, Erik C. Cook
8:15
am
–10:15
am
, R
oom
303
Platform
Membrane Pumps, Transporters,
and Exchangers II
Co-Chairs
Hanne Poulsen, University of Aarhus, Denmark
Lei Zheng, University of Texas Houston Medical School
2160-P
lat
8:15
am
TRANSPORT PATHWAY IN CU
+
P-TYPE ATPASES.
Magnus Andersson
, Daniel Mattle, Oleg Sitsel, Anna Marie Nielsen,
Erik Lindahl, Stephen H. White, Poul Nissen, Pontus Gourdon
2161-P
lat
8:30
am
cpow
travel
awardee
SOMATIC MUTATIONS IN THE NA,K-ATPASE CAN CAUSE
HYPERTENSION.
Hanne Poulsen
, Elena Azizan, Poul Nissen, Morris Brown
2162-P
lat
8:45
am
GLUTATHIONYLATION OF THE
Β
1 SUBUNIT PREVENTS THE
E1NA3 TO E2P FORWARD REACTION IN THE NA
+
, K
+
ATPASE.
Alvaro Garcia
, Chia-Chi Liu, Ronald Clarke, Helge Rasmussen
2163-P
lat
9:00
am
DISCOVERY OF ENZYME MODULATORS VIA HIGH-
THROUGHPUT TIME-RESOLVED FRET IN LIVING CELLS.
Simon J. Gruber
, Razvan L. Cornea, Kurt C. Peterson,
Gregory D. Gillispie, Seth L. Robia, David D. Thomas
2164-P
lat
9:15
am
MOLECULAR BASIS FOR SODIUM VERSUS CALCIUM BINDING
IN THE SODIUM-CALCIUM EXCHANGER.
Fabrizio Marinelli
,
José D. Faraldo-Gómez
2165-P
lat
9:30
am
STRUCTURE OF TRIMERIC CALCIUM/PROTON ANTIPORTER
PROTEIN YFKE REVEALS THE MECHANISMS OF CALCIUM
EFFLUX AND ITS PH REGULATION.
Lei Zheng
2166-P
lat
9:45
am
FUNCTIONAL RECONSTITUTION OF THE MITOCHONDRIAL
CA
2+
/H
+
ANTIPORTER LETM1.
Ming-Feng Tsai
, Christopher Miller
2167-P
lat
10:00
am
FOLDING AND ASSOCIATION OF HUMAN UNCOUPLING
PROTEIN-1 IN BIOLOGICAL MEMBRANES: EVIDENCE FOR
MULTIMERIC FUNCTIONAL FORMS.
Tuan Hoang
,
Matthew David Smith, Masoud Jelokhani-Niaraki
8:15
am
–10:15
am
, R
oom
304
Platform
Protein-Nucleic Acid Interactions II
Co-Chairs
Mark Williams, Northeastern University
Fredrik Westerlund, Chalmers University of Technology, Sweden
2168-P
lat
8:15
am
PROBING PHYSICAL PROPERTIES OF A DNA-PROTEIN
COMPLEX USING NANOFLUIDIC CHANNELS. Karolin Frykholm,
Mohammadreza Alizadehheidari, Joachim Fritzsche, Jens Wigenius,
Philip Nevin, Joshua Araya, Penny Beuning, Mauro Modesti, Fredrik Persson,
Fredrik Westerlund
2169-P
lat
8:30
am
DYNAMICS OF NAP1-ASSISTED NUCLEOSOME ASSEMBLY
IMAGED WITH HIGH-SPEED ATOMIC FORCE MICROSCOPY.
Allard Katan
, Rifka Hoogeboom-Vlijm, Alexandra Lusser,
Cees Dekker
2170-P
lat
8:45
am
CHARACTERIZING THE STRUCTURE AND FUNCTION OF
THE N-TERMINUS OF SCHIZOSACCHAROMYCES POMBE
CDC5, A PRE-MRNA SPLICING FACTOR.
Scott E. Collier
,
Dungeng Peng, Markus Voehler, Nicholas Reiter, Melanie Ohi
2171-P
lat
9:00
am
CONDENSATION OF DNA MEDIATED BY THE BACTERIAL
CENTROMERE BINDING PROTEIN SPO0J/PARB.
Cesar L. Pastrana, James A. Taylor, Mark S. Dillingham,
Fernando
Moreno-Herrero
