171
Biophysical Society 58
th
Annual Meeting, San Francisco, California
W
E
D
N
E
S
D
A
Y
1:00
pm
–3:00
pm
, R
oom
132/133
Platform
Molecular Dynamics II
Co-Chairs
Emad Tajkhorship, University of Illinois at Urbana-Champaign
Pengfei Tian, Niels Bohr Institute, Denmark
3233-P
lat
1:00
pm
TRANSCRIPTION FACTOR BINDING AND SLIDING STUDIED
USING MICROSCOPIC AND MESOSCOPIC MODELS.
Anel Mahmutovic
3234-P
lat
1:15
pm
SIMULATION OF THE CONFORMATIONAL TRANSITION
PATHWAY FOR THE ACTIVATION OF FULL-LENGTH C-SRC
KINASE USING THE STRING METHOD.
Mikolai Fajer
,
Yilin Meng, Benoit Roux
3235-P
lat
1:30
pm
EXPLORING PKA VALUES FOR BURIED RESIDUES IN
MEMBRANE BILAYERS USING CONSTANT PH MOLECULAR
DYNAMICS SIMULATIONS.
Afra Panahi
, Charles L. Brooks, III
3236-P
lat
1:45
pm
ROBUST ESTIMATION OF DIFFUSION-OPTIMIZED ENSEMBLES
FOR ENHANCED SAMPLING.
Pengfei Tian
, Sigurður Jónsson,
Jesper Ferkinghoff-Borg, Sergei Krivov, Kresten Lindorff-Larsen,
Wouter Boomsma
3237-P
lat
2:00
pm
DRIVEN ADAPTIVE-BIAS SCHEME: A HYBRID FREE ENERGY
METHOD FOR BIOMOLECULAR SYSTEMS WITH COMPLEX
ENERGY LANDSCAPES.
Mahmoud Moradi
, Emad Tajkhorshid
3238-P
lat
2:15
pm
GOING BACKWARD: AN EFFICIENT MULTISCALE APPROACH
USING REVERSE TRANSFORMATION.
Tsjerk A. Wassenaar
,
Kristyna Pluhackova, Rainer Böckmann, Siewert J. Marrink,
D. Peter Tieleman
3239-P
lat
2:30
pm
MIXING AND MATCHING SIMULATIONS AT DIFFERENT
RESOLUTIONS.
Manuel N. Melo
, Niculae Goga, Alexander de Vries,
Herman Berendsen
3240-P
lat
2:45
pm
CAVEOLIN IN BILAYERS: CAN THE INTRAMEMBRANE
U-SHAPED CONFORMATION REALLY EXIST.
Huan Rui
,
Kyle T. Root, Jinwoo Lee, Kerney Jebrell Glover, Wonpil Im
1:00
pm
–3:00
pm
, R
oom
303
Platform
Ligand-gated Channels II
Co-Chairs
Marc Delarue, Institut Pasteur, France
Crina Nimigean, Weill Cornell Medical College
3241-P
lat
1:00
pm
education
travel
awardee
COORDINATED MOVEMENTS DURING ASIC1A ACTIVITY.
Gaetano Bonifacio
, Claudia Suenaga lelli, Stephan Kellenberger
3242-P
lat
1:15
pm
OPTOCHEMICAL CONTROL OF ENGINEERED TRIMERIC
P2X RECEPTORS AND ACID-SENSING ION CHANNELS.
Liam E. Browne
, João P. M. Nunes, Joan Sim, Vijay Chudasama,
Laricia Bragg, Stephen Caddick, R. Alan North
3243-P
lat
1:30
pm
X-RAY STRUCTURES OF THE OPEN AND RESTING FORMS OF
THE SAME BACTERIAL PENTAMERIC LIGAND-GATED ION
CHANNEL. Ludovic Sauguet, Azadeh Shahsavar, Frederic Poitevin,
Christele Huon, Anais Menny, Akos Nemecz, Ahmed Haouz,
Jean-Pierre Changeux, Pierre-Jean Corringer,
Marc Delarue
3244-P
lat
1:45
pm
STRUCTURAL BASIS FOR ALLOSTERIC COUPLING AT THE
MEMBRANE-PROTEIN INTERFACE IN GLIC. Phanindra Velisetty,
Sreevatsa V. Chalamalasetti,
Sudha Chakrapani
3245-P
lat
2:00
pm
CALCIUM-DEPENDENT GATING IN MTHK K
+
CHANNELS
OCCURS AT THE SELECTIVITY FILTER.
David J. Posson
,
Radda Rusinova, Olaf S. Andersen, Crina M. Nimigean
3246-P
lat
2:15
pm
CLOSED STATE COUPLED C-TYPE INACTIVATION IN BK
CHANNELS.
Jiusheng Yan
, Wei Wang, Richard W. Aldrich
3247-P
lat
2:30
pm
TPC1 IS A PROTON PERMEABLE CHANNEL THAT CAN BE
INDEPENDENTLY ACTIVATED BY CYTOSOLIC CALCIUM
OR NAADP.
Samantha J. Pitt
, Andy Lam, Antony Galione,
Rebecca Sitsapesan
3248-P
lat
2:45
pm
SKA-111, A POSITIVE KCA CHANNEL GATING MODULATOR
WITH SELECTIVITY FOR KCA3.1.
Nichole T. Coleman
,
Brandon M. Brown, Aida O. Viguera, Ralf Köhler, Heike Wulff
1:00
pm
–3:00
pm
, R
oom
304
Platform
Computational Systems Biology and Cellular
Network
Co-Chairs
Carlos Lopez, Vanderbilt University School of Medicine
Eric Deeds, University of Kansas
3249-P
lat
1:00
pm
INTEGRATED 3D SIMULATION OF CARDIOMYOCYTE
REVEALED THE DISTINCT FUNCTIONAL CHARACTERISTICS
BETWEEN SUBSARCOLEMMAL AND INTERFIBRILLAR
MITOHONDRIA.
Asuka Hatano
, Jun-ichi Okada, Takumi Washio,
Toshiaki Hisada, Seiryo Sugiura
3250-P
lat
1:15
pm
PYSB: A MODELING FRAMEWORKTO EXPLORE BIOCHEMICAL
SIGNALING PROCESSES AND CELL-DECISIONS.
Carlos F. Lopez
,
Shawn P. Garbett
3251-P
lat
1:30
pm
THE EVOLUTION OF CROSSTALK IN SIGNALING NETWORKS.
Eric J. Deeds
, Michael A. Rowland
3252-P
lat
1:45
pm
COMPUTATIONAL MODELING OF BIOFILM STRUCTURE
AND FUNCTIONS WITH BACTERIA MOTILITY FEATURE
AND EXPERIMENT VALIDATION.
Jia Zhao
, Qi Wang
3253-P
lat
2:00
pm
IDENTIFYING ACTIVE NEURONS FROM IN VIVO 2-PHOTON
CALCIUM IMAGING OF THE BRAIN VIA PIXEL CORRELATION
ANALYSIS AND REGION-GROWING SEGMENTATION.
Jean-Francois Desjardins
, Loïs S. Miraucourt, Edward S. Ruthazer,
Paul W. Wiseman
