176
Biophysical Society 58
th
Annual Meeting, San Francisco, California
3325-P
os
B
oard
#B53
EXPLORING THE ENERGY LANDSCAPE THROUGH ANCESTRAL
PROTEINS.
Shion An
, Kathryn M. Hart, Susan Marqusee
3326-P
os
B
oard
#B54
THE EFFECTIVE TEMPERATURE OF MUTATIONS: A GENERAL
MECHANISM FOR THE CONGRUENT EVOLUTION OF
ROBUSTNESS.
Gergely J. Szöllősi
, Imre Derényi
3327-P
os
B
oard
#B55
MOONLIGHTING PROTEINS.
Constance Jeffery
, Matt Mani,
Vaishak Amblee, Chang Chen
Dynamics of Ligand Binding
(Boards #B56–#B84)
3328-P
os
B
oard
#B56
THIOL LABELING REVEALS PRESENCE OF CRYPTIC BINDING
SITES IN BETA-LACTAMASE.
Eric Bolin
, Brendan Maguire,
Gregory Bowman, Susan Marqusee
3329-P
os
B
oard
#B57
STRUCTURAL DYNAMICS STUDIES OF FATTY ACID BINDING
PROTEIN-4 BY SOLUTION NMR SPECTROSCOPY.
Adedolapo Ojoawo,
Choua Xiong
, Kim N. Ha
3330-P
os
B
oard
#B58
minority
affairs
travel
awardee
INSIGHTS INTO THE CYCLIC NUCLEOTIDE SELECTIVITY
MECHANISM OF CYCLIC GMP DEPENDENT PROTEIN KINASE
II.
James Campbell
, Gilbert Huang, Albert Reger, Todd Link,
John Ladbury, Choel Kim
3331-P
os
B
oard
#B59
EFFECTS OF LIGAND BINDING ON THE RIGIDITY AND
MOBILITY OF PROTEINS: AN EXPERIMENTAL AND
COMPUTATIONAL APPROACH.
Jack Heal
, Claudia Blindauer,
Robert B. Freedman, Rudolf Roemer
3332-P
os
B
oard
#B60
BRIDGING SIMULATIONS AND CALORIMETRY:
COMPUTATIONAL STUDIES OF BINDING THERMODYNAMICS
AND ENTROPY-ENTHALPY TRANSDUCTION.
Michael K. Gilson
,
Andrew T. Fenley, Hari Muddana
3333-P
os
B
oard
#B61
DIFFERENTIAL RESPONSES OF MSH2/6 AND DAMAGED DNA
PROBED BY MOLECULAR DYNAMICS.
Freddie R. Salsbury, Jr
,
Lacramioara Negureanu
3334-P
os
B
oard
#B62
ATOMIC RESOLUTION MECHANISM OF CD44-HYALURONAN
PROTEIN-CARBOHYDRATE BINDING. Christina E. Faller,
Amanda J. Favreau,
Olgun Guvench
3335-P
os
B
oard
#B63
A MOLECULAR DYNAMICS INVESTIGATION OF THE
BACTERIAL CIS-PRENYL TRANSFERASES: PERSPECTIVES ON
CONFORMATIONAL FLEXIBILITY AND CHAIN ELONGATION
MECHANISMS.
Meekyum O. Kim
, Ferran Feixas-Gerones,
Eric Oldfield, J. Andrew McCammon
3336-P
os
B
oard
#B64
STUDY OF THE DYNAMIC AND THERMODYNAMIC CALCIUM
INDUCED TRANSITION IN THE DOWNSTREAM REGULATORY
ELEMENT ANTAGONIST MODULATOR (DREAM) USING
PHOTOTHERMAL BEAM DEFLECTION (PBD).
Walter G. Gonzalez
,
Jaroslava Miksovska
3337-P
os
B
oard
#B65
SOLID-STATE NMR CHARACTERIZATION OF S31N M2
TRANSMEMBRANE DOMAIN BOUND TO NOVEL ADAMAN-
TANES WITH PERSISTENT
IN VITRO
EFFICACY.
Anna K. Wright
,
Ivan Hung, Christina Tzitzoglaki, Harris Ioannidis, David D. Busath,
Antonios Kolocouris, Timothy A. Cross
3338-P
os
B
oard
#B66
SINGLE MOLECULE FRET STUDIES OF THE NMDA RECEPTOR
USING UNNATURAL AMINO ACIDS.
Drew Dolino
, David Cooper,
Swarna Ramaswamy, Christy Landes, Vasanthi Jayaraman
3339-P
os
B
oard
#B67
HEME-TRANSFER MECHANISM OF STRUCTURALLY SIMILAR
ISD NEAT DOMAINS OF STAPHYLOCOCCUS AUREUS
EXHIBITING DIFFERENT AFFINITIES FOR HEME.
Yoshitaka Moriwaki
, Tohru Terada, Jose M. M. Caaveiro,
Yousuke Takaoka, Itaru Hamachi, Kouhei Tsumoto, Kentaro Shimizu
3340-P
os
B
oard
#B68
EXPLORING HOW PHOSPHORYLATION INFLUENCES C-I IN-
TERACTION AND CALCIUM SENSITIVITY OF TROPONIN BY
MOLECULAR DYNAMICS SIMULATIONS.
Yuanhua Cheng
,
Steffen Lindert, Peter Kekenes-Huskey, Vijay S. Rao, Paul R.
Rosevear, J. Andrew McCammon, Andrew McCulloch, Michael Regnier
3341-P
os
B
oard
#B69
A COMPLETE CONFIGURATIONAL ENSEMBLE APPROACH TO
EXPAND LSD1/COREST DRUGGABILITY.
James C. Robertson
,
Nate C. Hurley, Julie M. Kneller, Nadeem A. Vellore, Andrea Mattevi,
Riccardo Baron
3342-P
os
B
oard
#B70
THE ACIDIC RESIDUES OF THE I
κ
B
α
PEST SEQUENCE ARE
RESPONSIBLE FOR “STRIPPING” NF
κ
B FROM DNA.
Holly E. Dembinski
, Elizabeth A. Komives
3343-P
os
B
oard
#B71
STRUCTURAL BASIS FOR CA
2+
SELECTIVITY OF A VOLTAGE-
GATED CALCIUM CHANNEL.
Lin Tang
, Tamer M. Gamal El-Din,
Jian Payandeh, Gilbert Q. Martinez, Teresa M. Heard, Todd Scheuer,
Ning Zheng, William A. Catterall
3344-P
os
B
oard
#B72
STRUCTURAL AND DYNAMIC FEATURES UNDERLIE THE
SWITCH OF LIGAND BINDING SPECIFICITY IN A TIAM1 PDZ
DOMAIN MUTANT.
Ernesto J. Fuentes
, Xu Liu, David C. Speckhard,
Tyson R, Shepherd
3345-P
os
B
oard
#B73
international
travel
awardee
TRANSTHYRETIN INDUCED AMYLOIDOSIS INTERACTIONS,
MECHANISMS AND POTENT DRUGS DESIGN.
Rafal Jakubowski
,
Piotr Skrzyniarz, Lukasz Peplowski, Wieslaw Nowak
3346-P
os
B
oard
#B74
A TEMPERATURE JUMP RELAXATION STUDY OF DYNAMICS
OF THERMOPHILIC LACTATE DEHYDROGENASE FROM TH.
MARITIMA.
Huo-Lei Peng
, Hua Deng, Robert Callender
3347-P
os
B
oard
#B75
STRUCTURAL AND FUNCTIONAL BASIS OF TOLLIP
ASSOCIATION TO THE ENDOSOMAL ADAPTOR PROTEIN
TOM1.
Mary K. Brannon
, Shuyan Xiao, Geoffrey Armstrong,
Kristen Fread, Carla V. Finkielstein, Daniel G. S. Capelluto
3348-P
os
B
oard
#B76
MODELING AND EXPERIMENTAL STUDY OF NHERF1 PDZ
DOMAIN SPECIFICITY.
Tatyana Mamonova
, Alessandro Bisello,
Peter A. Friedman
