41
Biophysical Society 58
th
Annual Meeting, San Francisco, California
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588-P
os
B
oard
#B343
A SMALL NUMBER OF CELLS IS SUFFICIENT TO TRIGGER A
CARDIAC ARRHYTHMIA: STOCHASTIC COMPUTATIONAL
STUDIES.
Aman Ullah
, Tuan M. Hoang-Trong, George S.B. Williams,
Jonathan W. Lederer, Mohsin S. Jafri
589-P
os
B
oard
#B344
RELATIVE CONTRIBUTION OF PURKINJE FIBERS TO CA
2+
-DE-
PENDENT ARRHYTHMIAS IN A MURINE MODEL OF CPVT.
Lucia Brunello
, Bjorn C. Knollmann, Paul M. L. Janssen, Sandor Gyorke
590-P
os
B
oard
#B345
THE METABOLIC MODULATOR PERHEXILINE INDUCES
CALCIUM-CYCLING DYSFUNCTION AND APOPTOSIS IN
CARDIOMYOCYTE SYNCYTIA. Alice N. Mitchell, Ryan Preece,
Karl Swann, Zaheer Yousef,
Christopher H. George
591-P
os
B
oard
#B346
INTRACELLULAR FREE ZINC ION INCREASE TRIGGERS
HYPERGLYCEMIA-INDUCED CARDIOMYOCYTE
DYSFUNCTION THROUGH ENDOPLASMIC RETICULUM
STRESS. Erkan Tuncay, Figen Amber Cicek, Aysegul Toy,
Belma Turan
592-P
os
B
oard
#B347
K
+
CHANNEL-INTERACTING PROTEIN 2 DEFICIENT MICE
HAVE A RATE DEPENDENT PROLONGATION OF LEFT
VENTRICULAR CA
2+
TRANSIENTS.
Soren Grubb
, Gary L. Aistrup,
Soren-Peter Olesen, Tobias Speerschneider, Kirstine Calloe, Morten B. Thomsen
593-P
os
B
oard
#B348
CALCIUM HANDLING IN EXPERIMENTAL MODELS OF
DOXORUBICIN AND RADIATION-INDUCED CARDIOTOXICITY.
Anna Llach
, Marianne Mazevet, Virginie Monceau, Philippe Matéo,
Jean-Pierre Bénitah, Marie-Catherine Vozenin, Eric Morel, Ana María Gómez
594-P
os
B
oard
#B349
education
travel
awardee
MECHANISMS OF ANTHRACYCLINE-INDUCED
DYSFUNCTION OF CALCIUM HANDLING PROTEINS IN THE
HEART.
Amy D. Hanna
, Alex Lam, Angela F. Dulhunty, Nicole A. Beard
595-P
os
B
oard
#B350
PREDICTIVE DRUG TOXICITY PROFILING USING A NEW
MODE OF CALCIUM SIGNAL ANALYSIS IN HUMAN
ES-DERIVED CARDIOMYOCYTES. Kimberley J. Lewis,
Sarah A. Marsh
, Christopher H. George
596-P
os
B
oard
#B351
A NOVEL FLUORESCENT EPAC-AGONIST REVEALS EPAC1
AND EPAC2 SUBCELLULAR LOCALIZATION IN CARDIOMYO-
CYTES.
Laetitia Pereira
, Jeffrey Erickson, Ju Chen, Donald M. Bers
597-P
os
B
oard
#B352
FUNCTIONALLY ISOLATED SARCOPLASMIC RETICULUM
MODEL: INTRINSIC REGULATION OF SR CA
2+
RELEASE AND
TETRACAINE EFFECT. Marina C. Monteiro, Rosana A. Bassani,
José W. Bassani
598-P
os
B
oard
#B353
FLUORESCENCE SIGNAL KINETICS OF A NEW CA
2+
PROBEBOUND TO CARDIAC RYANODINE RECEPTORS POINT
TO MICRO-DOMAIN DETECTION OF CA
2+
. Xiao-Hua Zhang,
Lars Cleemann
, Martin Morad
599-P
os
B
oard
#B354
CALCIUM-INDUCED REDOX MICRODIMAINS AT THE
ER-MITOCHONDRIAL INTERFACE.
David M. Booth
,
Balázs Enyedi, Miklós Geiszt, Péter Várnai, György Hajnóczky
600-P
os
B
oard
#B355
BUFFER- AND DIFFUSION-MEDIATED CALCIUM
CONCENTRATION FLUCTUATIONS ACCELERATE THE
STOCHASTIC DYNAMICS OF CALCIUM-TRIGGERED
EVENTS.
Seth H. Weinberg
, Gregory D. Smith
601-P
os
B
oard
#B356
WNT-11 SIGNALING IN CARDIOMYOCYTES.
Paulina Wakula
,
Gudrun Antoons, Snjezana Radulovic, Senka Ljubojevic,
Michael Sereinigg, Burkert M. Pieske, Frank R. Heinzel
602-P
os
B
oard
#B357
INHIBITION OF THE NA
+
/CA
2+
EXCHANGER (NCX) IMPROVES
CARDIOMYOCYTE CONTRACTILE DYSFUNCTION IN A RAT
MODEL WITH COMPENSATED RENAL FAILURE AND HEART
FAILURE WITH PRESERVED EJECTION FRACTION.
Uwe Primessnig
, Alexander Hoell, Susanne Pfeiffer, Thomas Rau,
Paulina Wakula, Burkert Pieske, Frank Heinzel
603-P
os
B
oard
#B358
ALTERATIONS OF NUCLEAR CA2
+-
DEPENDENT SIGNALLING
IN HEART FAILURE.
Senka Ljubojevic
, Snjezana Radulovic, Simon Sedej,
Jens Kockskaemper, Burkert Pieske
604-P
os
B
oard
#B359
UROCORTIN 2 PROTECTS AGAINST PACING-INDUCED
ALTERNANS VIA PHOSPHORYLATION OF PHOSPHOLAMBAN
IN CARDIAC MYOCYTES FROM NORMAL AND FAILING
HEARTS.
Stefanie Walther
, Joshua N. Edwards, Florentina Pluteanu,
Susanne Renz, Kurt Schmidt, Burkert Pieske, Jens Kockskaemper,
Lothar A. Blatter
605-P
os
B
oard
#B360
NOS1AP MODULATES INTRACELLULAR CA2
+
IN CARDIAC
MYOCYTES AND IS UP-REGULATED IN DYSTROPHIC
CARDIOMYOPATHY.
Adriana V. Treuer
, Daniel R. Gonzalez
606-P
os
B
oard
#B361
PGZ REVERSES CARDIAC DYSFUNCTION IN DYSTROPHIC
MICE. Francisco Altamirano, Juan Kolster, José Adams,
Jose R. Lopez
607-P
os
B
oard
#B362
A MARKOV-STATE MODEL FOR THE REGULATION OF THE
SARCOPLASMIC RETICULUMCA
2+
ATPASE BY PHOSPHOLAMBAN.
Peter M. Kekenes-Huskey
, Andy Edwards, Johan Hake,
Anouchka Michailova, James A. McCammon, Andrew McCulloch
608-P
os
B
oard
#B363
OPTIMAL RETICULATED COVERAGE OF THE SARCOPLASMIC
RETICULUM.
Zana A. Coulibaly
, Leighton T. Izu, Bradford E. Peercy
Cardiac, Smooth, and Skeletal Muscle
Electrophysiology I (Boards #B364–#B390)
609-P
os
B
oard
#B364
SPECIES-SPECIFIC COMPARISON OF THE CARDIAC SODIUM/
POTASSIUM PUMP BASED ON A MINIMAL BIOPHYSICAL
MODEL.
Alexandre Lewalle
, Steven Niederer, Nic Smith
610-P
os
B
oard
#B365
INTERMITTENT EARLY AFTERDEPOLARIZATIONS CAUSED
BY BISTABILITY.
Yuanfang Xie
, Zhandi Liao, Daisuke Sato,
Yohannes Shiferaw, Donald M. Bers
611-P
os
B
oard
#B366
DIABETIC HYPERGLYCEMIA ACUTELY AFFECTS ACTION
POTENTIALS AND IONIC CURRENTS THROUGH CAMKII
ACTIVATION ON RAT VENTRICULAR MYOCYTES.
Zhandi Liao
,
Donald M. Bers
