43
Biophysical Society 58
th
Annual Meeting, San Francisco, California
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633-P
os
B
oard
#B388
EVALUATION OF OPTICAL UPSTROKE MORPHOLOGY IN
THE RABBIT HEART: OPTICAL MAPPING AND TRANSMURAL
MICROELECTRODE RECORDINGS.
Rūta Vosyliūtė
,
Regina Mačianskienė, Irma Martišienė, Antanas Navalinskas,
Rimantas Treinys, Birutė Vaidelytė, Gintautė Rutkauskaitė, Jonas Jurevičius
634-P
os
B
oard
#B389
MECHANISMS UNDERLYING NA
+
/K
+
-ATPASE INHIBITION-IN-
DUCED MITOCHONDRIAL DYSFUNCTION AND ABNORMAL
ACTION POTENTIALS. Qince Li,
Lufang Zhou
635-P
os
B
oard
#B390
INHIBITION OF MITOCHONDRIAL NA
+
/CA
2+
EXCHANGER
SUPPRESSES ISCHEMIA/REPERFUSION-INDUCED REENTRY
IN MONOLAYERS OF CARDIOMYOCYTES.
Soroosh Solhjoo
,
Brian O’Rourke
Excitation-Contraction Coupling I
(Boards #B391–#B420)
636-P
os
B
oard
#B391
RAPTOR ABLATION IN SKELETAL MUSCLE AFFECTS THE
STRUCTURE AND FUNCTION OF THE EXCITATION-
CONTRACTION COUPLING MACROMOLECULAR COMPLEX.
Ruben Lopez, Barbara Mosca, Leda Bergamelli, Markus A. Ruegg,
Florian C. Bentzinger, Michael N. Hall, Susan Treves,
Francesco Zorzato
637-P
os
B
oard
#B392
MODIFICATION OF CARDIAC RYANODINE RECEPTOR
GATING BY A PEPTIDE FROM THE CENTRAL DOMAIN OF
THE RYR2. Andrea Faltinova,
Alexandra Zahradnikova
638-P
os
B
oard
#B393
ULTRASTRUCTURAL QUANTIFICATION OF ELECTRON-DENSE
STRINGS IN THE SARCOPLASMIC RETICULUM OF RAT HEART
CELLS. Lin-Lin Li, Xue-Xin Fan,
Shi-Qiang Wang
639-P
os
B
oard
#B394
RESOLVING THE CALCIUM RELEASE MACHINERY OF
MAMMALIAN FAST- AND SLOW-TWITCH SKELETAL
MUSCLE.
Isuru D. Jayasinghe
, Michelle Munro, David Baddeley,
Bradley S. Launikonis, Christian Soeller
640-P
os
B
oard
#B395
LETHAL EXERTIONAL STROKES IN RYR1
Y522S/WT
AND CASQ1-
NULL MICE ARE PREVENTED BY DRUGS USED TO TREAT
MALIGNANT HYPERTHERMIA IN HUMANS.
Antonio Michelucci
,
Alessandro De Marco, Laura Pietrangelo, Cecilia Paolini,
Susan L. Hamilton, Feliciano Protasi
641-P
os
B
oard
#B396
CLIC-2 DETERMINES FKBP12 AND FKBP12.6 ASSOCIATION
WITH RYANODINE RECEPTOR CALCIUM RELEASE CHANNELS.
Gregory A. Steele, Nicole A. Beard, Philip G. Board,
Angela F. Dulhunty
642-P
os
B
oard
#B397
DYAD CONTENT IS REDUCED IN CARDIAC MYOCYTES OF
MICE WITH IMPAIRED CALMODULIN REGULATION OF
RYR2.
Manuela Lavorato
, Huang Taiqin, Venkat Ramesh Iyer,
Gerhard Meissner, Clara Franzini-Armstrong
643-P
os
B
oard
#B398
SILENCING RYR3 ELIMINATES PARAJUNCTIONAL FEET AND
CA SPARKS IN ZEBRA FISH TAIL MYOTOMES.
Stefano Perni
,
Clara Franzini-Armstrong, Stephen Hollingworth, Stephen M. Baylor
644-P
os
B
oard
#B399
CHEMICAL UNCOUPLING THE DHPR-RYR1 COMPLEX BY
SUBSTITUTED HALOGENATED BIPHENYLS AND
DIPHENYLETHERS.
Yassaman Niknam
, Wei Feng,
Gennady Cherednichenko, Yao Dong, Isaac Pessah
645-P
os
B
oard
#B400
ALTERED ION CHANNEL PROPERTIES OF RYANODINE
RECEPTOR FROM HEART MICE LACKING CALSTABIN2.
Nathalie Saint
, Albano C. Meli, Valerie Scheuermann, Alain Lacampagne
646-P
os
B
oard
#B401
MODULATION OF DHPR INACTIVATION BY RYR1 ACTIVITY
IN MOUSE SKELETAL MUSCLE FIBERS. Zoita Andronache,
Werner Melzer
647-P
os
B
oard
#B402
CA
2+
INFLUX MEDIATED BY REVERSE MODE OF NA
+
/CA
2+
EXCHANGER IS ENHANCED IN MALIGNANT HYPERTHERMIA
SKELETAL MUSCLE.
Francisco Altamirano
, Jose M. Eltit, Isaac Pessah,
Paul D. Allen, Jose R. Lopez
648-P
os
B
oard
#B403
MYOFILAMENT CA
2+
DESENSITIZATION IS ASSOCIATED WITH
REDUCED L-TYPE CA
2+
CHANNEL ACTIVITY
MEDIATED BY NEURONAL NITRIC OXIDE SYNTHASE IN LEFT
VENTRICULAR MYOCYTES FROM MURINE HEARTS. Yue Wang,
Chun Zi Jin, Sung Joon Kim,
Yin Hua Zhang
649-P
os
B
oard
#B404
RGK PROTEINS INHIBIT SLOW, DEPOLARIZATION-
DEPENDENT CA
2+
ENTRY INTO CULTURED MYOTUBES.
Christin F. Romberg, Donald Beqollari, Ulises Meza,
Roger A. Bannister
650-P
os
B
oard
#B405
EXPRESSION OF THE EMBRYONIC CAV1.1 SPLICE VARIANT
IN ADULT MICE ALTERS EXCITATION-CONTRACTION
COUPLING BUT DOES NOT CAUSE DYSTROPHIC MYOTONIA.
Nasreen Sultana
, Ariane Benedetti, Monika Sztretye, Beatrix Dienes,
Peter Szentesi, Petronel Tuluc, Serena Quarta, Gerald J. Obermair,
Christoph Schwarzer, Michaela Kress, Laszlo Csernoch, Bernhard E. Flucher
651-P
os
B
oard
#B406
THE DHPR CALCIUM CURRENT IN MAMMALIAN SKELETAL
MUSCLE: PHYSIOLOGICAL NECESSITY OR TOLERATED
EVOLUTIONARY REMNANT? Anamika Dayal,
Kai Schrötter
,
Werner Melzer, Christoph Schwarzer, Manfred Grabner
652-P
os
B
oard
#B407
CA
2+
UPTAKE BY THE TUBULAR (T-) SYSTEM MEMBRANE OF
RAT FAST-TWITCH FIBRES.
Tanya R. Cully
, Joshua N. Edwards,
Thomas R. Shannon, Bradley Launikonis
653-P
os
B
oard
#B408
POSSIBLE ROLE FOR THE PHOSHORYLATED TAIL IN
RETAINING CSQ2 TO SPECIFIC SITES WITHIN THE
SECRETORY PATHWAY.
Cristine Smoczer
, Naama H. Sleiman,
Steven Cala
654-P
os
B
oard
#B409
MICROTUBULE INTEGRITY IS ESSENTIAL TO JUNCTIONAL
SR PROTEIN DELIVERY.
Naama H. Sleiman
, Cristine Somczer,
Steven E. Cala
655-P
os
B
oard
#B410
PROTON FLUXES ACROSS THE TUBULAR (T-) SYSTEM
MEMBRANE OF RAT FAST-TWITCH FIBRES. Bradley S. Launikonis,
Tanya R. Cully
, Laszlo Csernoch, D. George Stephenson
