45
Biophysical Society 58
th
Annual Meeting, San Francisco, California
S
A
T
U
R
D
A
Y
F
R
I
D
A
Y
U
N
D
A
Y
680-P
os
B
oard
#B435
AUTOMATED PATCH CLAMPING OF 384 CELLS AT ONCE FOR
MASSIVELY PARALLEL ION CHANNEL SCREENING.
Andrea Bruggemann
, Claudia Haarmann, Timo Stengel, Marius Vogel,
Juergen Steindl, Max Mueller, Johannes Stiehler, Michael George,
Niels Fertig
681-P
os
B
oard
#B436
SODIUM CHANNEL PEPTIDE NEUROTOXIN STUDIES USING
A HIGH THROUGHPUT ELECTROPHYSIOLOGY PLATFORM
AND VERY LONG ASSAY WINDOWS.
Xin Jiang
, Jeffrey Webber,
Trisha Mitlo, Edward Verdonk, James Costantin
682-P
os
B
oard
#B437
SEARCHING FOR THE INTERACTION SITES OF THE BETA1
SUBUNIT WITH THE VOLTAGE-SENSING DOMAINS OF SODI-
UM CHANNELS USING LRET.
Tomoya Kubota
, Bobo Dang, Rocio
K. Finol-Urdaneta, Jérôme J. Lacroix, Ludivine Frezza, Robert J. French,
Stephen B. H. Kent, Ana M. Correa, Francisco Bezanilla
683-P
os
B
oard
#B438
TRACKING VOLTAGE-DEPENDENT CONFORMATIONAL
CHANGES OF THE VSD IN NAV WITH LRET.
Tomoya Kubota
,
Pedro Brugarolas, Bobo Dang, Rocio K. Finol-Urdaneta, Ludivine Frezza,
Robert J. French, Stephen B. H. Kent, Francisco Bezanilla, Ana M. Correa
Voltage-gated Ca Channels I
(Boards #B439–#B456)
684-P
os
B
oard
#B439
OBSERVATION OF “REMOTE KNOCK-ON”, A NEW PER-
MEATION-ENHANCEMENT MECHANISM IN ION CHAN-
NELS.
Dmitry G. Luchinsky
, Rodrigue Tindjong, Igor Kaufman, Peter
V. E. McClintock, Igor A. Khovanov, Bob S. Eisenberg
685-P
os
B
oard
#B440
A MUTATIONAL AND COMPUTATIONAL STUDY OF WATER
AND ION MOVEMENT THROUGH THE S6 BUNDLE-CROSS-
ING OF CAV1.2 CHANNEL.
Roman Shirokov
686-P
os
B
oard
#B441
POISSON-FERMI MODEL OF A CALCIUM CHANNEL: CORRE-
LATIONS AND DIELECTRIC COEFFICIENT ARE COMPUTED
OUTPUTS.
Bob Eisenberg
, Jinn-Liang Liu
687-P
os
B
oard
#B442
THE FUNCTIONAL HETEROGENEITY OF THE HUMAN CA
V
1.2
VOLTAGE SENSORS.
Antonios Pantazis
, Nicoletta Savalli, Daniel Sigg,
Alan Neely, Riccardo Olcese
688-P
os
B
oard
#B443
FUNCTIONAL INTERACTION BETWEEN THE N-TERMINI OF
MURINE L-TYPE CALCIUM CHANNEL CA
V
1.2- AND
β
-SUBUNIT
SPLICE VARIANTS. Ajay K. Singh, Elza Kuzmenkina, Jan Matthes,
Stefan Herzig
689-P
os
B
oard
#B444
GATING PROPERTIES OF CAV1.3 CALCIUM CHANNELS: IN-
SIGHT FROM ALTERNATIVE SPLICING AND HUMAN MUTA-
TIONS.
Andreas Lieb
, Nadine Ortner, Alexandra Pinggera, Elena A.
Azizan, Morris J. Brown, Petronel Tuluc, Jörg Striessnig
690-P
os
B
oard
#B445
HILL ANALYSIS OF ION CHANNEL ACTIVATION: THEORY
AND PRACTICE.
Daniel Sigg
, Ru-Chi Shieh, Antonios Pantazis,
Nicoletta Savalli, Riccardo Olcese
691-P
os
B
oard
#B446
DOMAIN-SPECIFIC GATING-MODIFIER TOXINS FOR
VOLTAGE-GATED CALCIUM CHANNELS.
Autoosa Salari
,
Vincent L. Baggett, Mirela Milescu
692-P
os
B
oard
#B447
THE
α
2
δ
SUBUNIT FACILITATES CA
V
1.2 CHANNEL ACTIVATION
BY REMODELING ITS FOUR VOLTAGE SENSOR DOMAINS.
Nicoletta Savalli
, Antonios Pantazis, Daniel Sigg, Alan Neely,
Riccardo Olcese
693-P
os
B
oard
#B448
A POPULATION DENSITY AND MOMENT-BASED APPROACH
TO MODELING DOMAIN CALCIUM-MEDIATED
INACTIVATION OF L-TYPE CALCIUM CHANNELS.
Xiao Wang
,
Kiah Hardcastle, Seth H. Weinberg, Gregory D. Smith
694-P
os
B
oard
#B449
MINIMIZED CELL USAGE FOR STEM CELL-DERIVED AND
PRIMARY CELLS ON AN AUTOMATED PATCH CLAMP
SYSTEM. Nadine Becker, Sonja Stoelzle-Feix, Sven Goepel,
David Guinot, Patrick Mumm, Claudia Haarmann, Daniela Malan,
Heribert Bohlen, Eugen Kossolov, Ralf Kettenhofen, Michael George,
Niels Fertig,
Andrea Bruggemann
695-P
os
B
oard
#B450
TESTING FOR DIRECT INTERACTIONS BETWEEN THE DHPR
AND THE RYR1 CYTOPLASMIC FOOT.
Hicham Bichraoui
,
Ong Moua, Alexander Polster, Tsutomu Tanabe, Simon Papadopoulos,
Kurt G. Beam
696-P
os
B
oard
#B451
MULTIPLE REGIONS INHIBIT EXPRESSION OF CAV1.1
CA
2+
CHANNELS IN NON-MUSCLE CELLS.
Alexander Polster
,
Tsutomu Tanabe, Ong Moua, Kurt G. Beam
697-P
os
B
oard
#B452
RESIDUES CRITICAL FOR VOLTAGE-SENSOR TRANSITIONS
DETERMINING GATING PROPERTIES OF CAV1.1.
Petronel Tuluc
,
Vladimir Yarov-Yarovoy, Bruno Benedetti, Bernhard E. Flucher
698-P
os
B
oard
#B453
DIFFERENTIAL STABILITY OF CA
V
β
2A
AND CA
V
β
3
IN A CA
V
1.2
CALCIUM CHANNEL COMPLEX.
Marta Campiglio
,
Felix Findeisen, Hyunil Jo, William F. DeGrado, Daniel L. Minor, Jr.,
Bernhard E. Flucher
699-P
os
B
oard
#B454
THE AMINO-TERMINI OF RGK PROTEINS DICTATE THE
MODE OF L-TYPE CA
2+
CHANNEL INHIBITION IN ADULT
SKELETAL MUSCLE.
Donald Beqollari
, Christin F. Romberg,
Ulises Meza, Symeon Papadopoulos, Roger A. Bannister
700-P
os
B
oard
#B455
PEGYLATED-CHOLESTEROL DECREASES THE AMPLITUDE
AND AUGMENTS TIME- AND VOLTAGE-DEPENDENT
INACTIVATION OF L-TYPE CA
2+
CURRENT OF A7R5
CELLS FROM RAT AORTA.
Rikuo Ochi
, Sukrutha Chettimada,
Sachin A. Gupte
701-P
os
B
oard
#B456
AKAP79/150-ANCHORED CAN AND PKA REGULATE
NEURONAL L-TYPE CALCIUM CHANNEL ACTIVITY AND
NFAT TRANSCRIPTIONAL SIGNALING.
Jonathan G. Murphy
,
Mark L. Dell’Acqua
