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Cumulative survival curve (Kaplan-Meier)

0

50

100

150

Time (days)

0,0

0,2

0,4

0,6

0,8

1,0

Cumulative Proportion Surviving

0 mg (N=109)

< 60 mg (N=156)

60 - 299 mg (N=533)

300 - 599 mg (N=156)

600 - 900 mg (N=52)

> 900 mg (N=82)

(Chi² = 42,4368 df = 5;

p < ,00001

)

P<0.00001

Survival

in

func.on

of the morphine equivalent dose

For >65y

pallia.ve

cancer pa.ents (died in the PCU-­‐ Leuven)