0
200
400
600
800
1000
1200
Mean OME dose (mg/day)
< 60 mg OME/dag (N=156)
60 - 299 mg OME/dag (N=533)
300 - 599 mg OME/dag
(N=156)
600 - 900 mg OME/dag (N=52)
> 900 mg OME/dag (N=82)
Fear for
opioid tolerance
can not justify
to withhold effective pain treatment
•
palliative care unit UH Leuven
•
>65y cancer patients (n = 1088)