1268 / 1578
/
• Retrospective analysis of 32 patients treated with 2 (n=29), 3
(n=2) or 4 (n=1) SBRT courses
SBRT for re-irradiation after SBRT
Ø
SBRT reirradiation for central recurrences
strongly discouraged!
Grade V
bleeding: n=3
Ø
All centrally located
Toxicity grade III - V
Peulen Radiother Oncol 2011
07.09.17
ESTRO SBRT 2017 - Matthias Guckenberger
39
/
Ø
A proposal for risk-adapted re-irradiation
Recurrent NSCLC
Palliative
intend
Asymptomatic
No RT
Symptomatic
10–15 x 3Gy
Potentially
curative intend
Peripheral
Small volume
(<2-3cm)
SBRT
Intermediate
volume
(<250cc)
Full-dose
CF-RT
Large volume
(>250cc)
Reduced
dose CF-RT
Central
< 40cc
central
overlap
Full dose
CF-RT
> 40cc
central
overlap
Reduced
dose CF-RT
07.09.17
ESTRO SBRT 2017 - Matthias Guckenberger
40