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Study characteristic published in

2015

Median age at diagnosis

(SEER)

Tumor entity Study question

Median age Maximum age

Breast

RT of mammaria interna

54 years 75 years

61 years

Breast

RT of mammaria interna

54 years 84 years

61 years

NSCLC

Dose escalation

Cetuximab

64 years 83 years

70 years

Rectal

Adjuvant CT after

neoadjuvent RCHT

62 years 68 years

68 years

Prostate

Duration AHT

72 years 85 years

66 years

Prostate

Hypofractionation of

RT

71 years 75 years

66 years

Recent randomized studies in

Radation Oncology

Ø

Lack of evidence covering elderly patients

ESTRO SBRT COURSE 2017 - Matthias Guckenberger

9

07.09.17

/

Overall population SEER > 65 years

Netherlands >75a

Surgery

RT

BSC

Surgery

RT

BSC

Surgery

RT

BSC

Raz Chest 2007

Shirvani IJROBP 2012 Haasbeek Ann Oncol 2012

11%

13%

29%

Treatment given to patients with curable

stage I NSCLC

Ø

1/3 of all patients >75 old remain untreated

ESTRO SBRT COURSE 2017 - Matthias Guckenberger

10

07.09.17