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INFORMS Philadelphia – 2015

485

2 - Transportation Optimizer System as Applied to Rail Car

Assignment Problem

Ilya Buzytsky, BIAS Intelligence, 7741 37th Ave NE, Seattle, WA,

98115, United States of America,

ilya@biasintelligence.com

BIAS Optimizer System was developed to address problems frequently

encountered in many transportation and distribution logistics applications. Its

objective is to find optimal solution to problems that can be formulated in terms

of supply/cost/demand configuration across large matrix representing a multi-

node network: The solution helps find an assignment that would meet the

demand supported by available supply across all nodes and satisfy all business

rules and constraints at the minimum cost.

3 - Diet Problem Pevisited

Fariborz Partovi, Professor, Drexel University, 33rd Chestnut

Street, Department of Decision Sciences, Philadlphia, PA, 19003,

United States of America,

Partovi@Drexel.edu

It has been close to seventy years since the Diet problem was introduced by

Stigler (Stigler 1945). However the problem with the classical Diet models is

based on lack of proper presentation of food preferences. For many people,

especially when they are eating outside their home, the content of the food as far

as nutrition is concern may be not as important as the taste of the food. In this

article we modify Diet problem using extensions of linear programming to

consider the above issues

WE19

19-Franklin 9, Marriott

Computational Optimization with Risk and

Uncertainty

Sponsor: Computing Society

Sponsored Session

Chair: John Siirola, Sandia National Laboratories, P.O. Box 5800,

MS 1326, Albuquerque, NM, 87185-1326, United States of America,

jdsiiro@sandia.gov

1 - Multistage Power Generation Capacity Expansion Models with

Different Risk Measures

Shu Tu, Lehigh University, H.S. Mohler Laboratory, 200 West

Packer, Bethlehem, PA, 18015, United States of America,

sht213@lehigh.edu

, Boris Defourny

We investigate different stochastic optimization formulations for the multistage

power generation capacity expansion problem. In particular, we focus on risk

measures whose parameters can be calibrated from market data.

2 - Exploiting Inter-scenario Information to Acclerate

Progressive Hedging

John Siirola, Sandia National Laboratories, P.O. Box 5800, MS

1326, Albuquerque, NM, 87185-1326, United States of America,

jdsiiro@sandia.gov,

Jean-paul Watson, David Woodruff

Progressive Hedging (PH) is a scalable and effective approach for solving large

stochastic programming problems through scenario-based decomposition.

However, PH is sensitive to key tuning parameters (notably rho) and for many

problems can exhibit slow convergence. In this work we present new approaches

for accelerating convergence and improved tuning by propagating key

information among scenarios.

3 - Production Planning under Uncertainty and Service

Level Constraints

Suleyman Karabuk, Associate Professor, University of Oklahoma,

School of Industrial and Sys Engineering, 202 W. Boyd St.,

Room 124, Norman, OK, 73019, United States of America,

karabuk@ou.edu

Consider a production planning problem with machine changeover and inventory

carrying costs, and service level constraints, where demand for products is

probabilistic. We formulate the problem as a multistage stochastic programming

model with recourse. The resulting model is very large scale even for trivially

small size instances. We develop an effective decomposition algorithm where

individual product sub problems are solved by a novel probabilistic dynamic

programming model.

WE21

21-Franklin 11, Marriott

Mathematical Modeling of HIV at the Cellular,

Individual, and Population Level

Sponsor: Health Applications

Sponsored Session

Chair: Eva Enns, Assistant Professor, Univeristy of Minnesota, 420

Delaware St. SE, Minneapolis, MN, 55408, United States of America,

eenns@umn.edu

1 - Mathematical Modeling of HIV Viral Dynamics and Immune

Response During Treatment Interruptions

Nargesalsadat Dorratoltaj, Virginia Tech, Room 392, Vet Med

Phase II., Blacksburg, VA, 24060, United States of America,

nargesd@vt.edu

, Josep Bassaganya-riera, Stanca Ciupe,

Stephen Eubank, Margaret O’dell, Hazhir Rahmandad,

Kaja Abbas

The objective of this study is to understand and predict HIV viral and immune

dynamics at the individual level during treatment interruption and low adherence

in developing AIDS. We use ordinary differential equations to build immune-viral

dynamics of HIV/AIDS during treatment interruption. The results of the

simulation show that the time that patients start treatment and for how long they

stay on treatment before interruption are unique predictor for time to progress to

AIDS.

2 - A Data-driven Approach to Understanding HIV Care Trajectories

and Retention in Care Challenges

Eva Enns, Assistant Professor, Univeristy of Minnesota,

420 Delaware St. SE, Minneapolis, MN, 55408,

United States of America,

eenns@umn.edu

Sub-optimal retention in HIV primary care is associated with increased risks of

mortality, detectable viral loads, and other complications compared to regular,

ongoing care; however, the standard dichotomous measures of retention (e.g.,

in/out of care) ignore the diversity and complexity of individual care trajectories.

In this talk, I describe a data-driven approach to understanding HIV care patterns

and how to incorporate complex care behaviors into mathematical models of HIV

interventions.

3 - Modeling a Bi-layer Contact Network of Injection Drug Users and

The Spread of Blood-borne Infections

Rui Fu, Stanford University, 74 Barnes CT, Stanford, CA, 94305,

United States of America,

ruif@stanford.edu,

Alexander

Gutfraind, Margaret L. Brandeau

Blood-borne infections can spread among injection drug users (IDUs) via risky

sexual and needle-sharing contacts. To accurately model the spread of such

contagions among IDUs, we build a bi-layer network that captures both types of

risky contacts. We present methodology for inferring important model

parameters. Such a model can be used to evaluate the efficacy of various

programs that aim to combat drug addiction and contain blood-borne diseases

among IDUs.

4 - Measuring the Potential Impact of Combination Prevention in

Sub-Saharan Africa

Amin Khademi, Assistant Professor, Clemson University, 130-D

Freeman Hall, Clemson, SC, 29634, United States of America,

khademi@clemson.edu,

Sunanth Anand

A public health approach to combination HIV prevention is advocated to contain

the epidemic in Sub-Saharan Africa. We explore the implications of universal

access to treatment along with HIV education scale-up in the region. We develop

an HIV transmission model, calibrate it with data from South Africa and simulate

the impacts of universal access to treatment along with HIV education scale-up on

HIV trends.

WE21