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INFORMS Philadelphia – 2015

76

3 - A Structural Approach to Community Detection in

Complex Networks

Song Chew, Associate Professor, Southern Illinois University

Edwardsville, Southern Illinois University-Edwardsville,

Edwardsville, IL, 62026, United States of America,

schew@siue.edu

We in this study develop a novel measure of community structure that gauges the

strengths and weaknesses of a proposed community structure against an ideal. In

addition, we present an algorithm that may, as it maximizes our measure, return

several alternative community structures for consideration. We provide several

examples to demonstrate use of our measure, and to illustrate applications of our

algorithm as well.

SB33

33-Room 410, Marriott

Applications of Markov Models to Medical Decision

Making Problems

Sponsor: Health Applications

Sponsored Session

Chair: M. Reza Skandari, University of British Columbia, Vancouver,

Vancouver, Canada,

reza.skandari@sauder.ubc.ca

1 - Evaluation of Breast Cancer Mammography Screening Policies

Considering Adherence Behavior

Maboubeh Madadi, University of Arkansas,

mmadadi@uark.edu

,

Shengfan Zhang, Louise Henderso

The efficacy of mammography screening guidelines is highly associated with

women’s compliance with these recommendations. Currently, none of the

existing policies take women’s behavior into consideration. In this study, we

develop a randomized partially observable Markov chain model to evaluate a

wide range of screening mammography policies, incorporating heterogeneity in

women’s adherence behaviors.

2 - Policy Approximation for Optimal Treatment Planning

Wesley Marrero, University of Michigan, 500 South State Street,

Ann Arbor, MI, 48109, United States of America,

wmarrero@umich.edu

, Mariel Lavieri, Jeremy B. Sussman,

Greggory J. Schell, Rodney A. Hayward

Markov decision process (MDP) models are powerful tools which enable the

derivation of optimal treatment policies, but may incur long computational times

and decision rules which are challenging to interpret by physicians. To reduce

complexity and enhance interpretability, we study how Poisson regression may be

used to approximate optimal hypertension treatment policies derived by a MDP

for maximizing a patient’s expected discounted quality-adjusted life years.

3 - Optimal Decision Making in a Markov Model with Parameter

Uncertainty: The Case of CKD

M. Reza Skandari, University of British Columbia-Vancouver,

Vancouver, BC, Canada,

reza.skandari@sauder.ubc.ca,

Steven Shechter, Nadia Zalunardo

We investigate a Markov decision process whose unknown transition parameters

are revealed partially through state observation. Decisions are made as the state

evolves. We use the model to study the optimal time to start preparing a type of

vascular access for chronic kidney disease patients who will need dialysis.

4 - Reinforcement Learning Algorithm for Blood Glucose Control in

Diabetic Patients

Mahsa Oroojeni Mohammad Javad, Northeastern University, 334

Snell Engineering, Northeastern Univ, Boston, United States of

America,

oroojeni.m@husky.neu.edu

, Stephen Agboola,

Kamal Jethwani, Ibrahim Zeid, Sagar Kamarthi

In this paper a reinforcement learning algorithm is proposed for regulating the

blood glucose level of Type I diabetic patients. In the proposed reinforcement

learning algorithm body weight and A1C level define the state of a diabetic

patient. For the agent, insulin dose levels constitute the actions. As a result of a

patient’s treatment, after each time step t, the patient receives a numerical reward

depending on the response of the patient’s health condition.

SB34

34-Room 411, Marriott

Smart Medical Prognosis and Decision Making

via Data Mining

Sponsor: Health Applications

Sponsored Session

Chair: Danica Xiao, PhD Candidate, University of Washington, Seattle,

3900 Northeast Stevens Way, Seattle, WA, 98195, United States of

America,

xiaoc@uw.edu

Co-Chair: Shouyi Wang, Assistant Professor, University of Texas at

Arlington, 3105 Birch Ave, Grapevine, TX, 76051, United States of

America,

shouyiw@uta.edu

1 - Does Specialization of Health Care Services Increase

Operational Efficiency?

Saied Samiedaluie, Postdoctoral Fellow, University of British

Columbia, E204 - 4500 Oak Street, BC Women’s Hospital,

Women’s Health Rese, Vancouver, BC, V6H 3N1, Canada,

saied.samiedaluie@gmail.com

, Vedat Verter

We study a health care network configuration problem considering two scenarios:

specialization versus generalization. We characterize the settings in which each

scenario is preferred in terms of minimizing the patient admission refusal rate.

Our results show that the decision of system configuration for a multi-hospital

network requires careful consideration of patient mix among arrivals, relative

length of stay of patients, and distribution of patient load between hospitals.

2 - A Model to Predict Depression among Diabetes Patients with

Application in Screening Policymaking

Haomiao Jin, University of Southern California, 3715 McClintock

Ave, GER 240, Los Angeles, CA, United States of America,

haomiaoj@usc.edu,

Shinyi Wu

About 30% of diabetes patients are suffering from depression, but nearly half of

them are undiagnosed. Universal screening improves depression diagnosis rates

but is labor-intensive. A machine learning model is developed to predict

depression among diabetes patients. The model is applied in a screening policy to

help healthcare providers to better prioritize the use of their resources and time

and increase efficiency in managing their patient population with depression.

3 - Data Mining Techniques Applied to the Study of Canines

with Disease

Zhenpeng Miao, Saint Joseph’s University, 5600 City Ave,

Philadelphia, PA, 19131, United States of America,

mmkuchi0@gmail.com,

Yingdao Qu, Virginia Miori

This paper, the third in a series, aims at providing models effective in predicting

the degree of pain and discomfort in canines suffering from osteoarthritis,

sarcoma, dermatitis and side effects of radiation treatments. The R programing

language and SAS JMP are used to clean data and execute multivariate analyses

to predict changes in different activity levels. The predictive models provide

information that can assist in effective diagnosis and medication of suffering dogs.

4 - Understanding Linear and Non Linear Brain Dynamics During

Manual Lifting Tasks

Awad Aljuaid, PhD Student, UCF, University of Central Florida

4000 Cent, Department of Industrial Engineering, Orlando, FL,

32816-2993, United States of America,

amjuaid@knights.ucf.edu

,

Waldemar Karwowski, Petros Xanthopoulos

The aim of this study is to test the change on different EEG measures during

various psychophysical lifting frequencies. High-density wireless dry cell EEG

device have been used to record brain signals. Twenty healthy males participated

in this experiment performing two physical lifting sessions psychophysical weight

lifting (low, medium, and high) and strength measurements (Isometric and

isokinetic). EEG recording at different brains locations are analyzed with linear

and non-linear methods.

SB33