S768
ESTRO 36
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for small fields. Furthermore a difference was observed
between profiles performed in head-foot or foot-head
direction (Figure 2). Dose rate dependence was found to
be <0.3% while dose per pulse dependence showed an
increasing trend but still <0.6% for a maximum dpp of 0.2
cGy/pulse. At the nominal operating voltage of 300 V the
Razor Nanochamber exhibits a field size dependence of
the polarity correction > 2% between the 1x1cm
2
and the
40x40cm
2
field. The OF values were compared with diode
and scintillator measurements and show a good agreement
for fields >20x20 mm
2
. For smaller fields the volume effect
is huge and leads to strongly underestimated values.
Conclusion
Razor chamber is an interesting option for small field
measurements. Its use in orthogonal configuration raises
some stem effect issues evident when measuring inline
profiles. More measurements are required in order to fully
characterize this ion-chamber.
EP-1440 Monte Carlo determination of scintillator
quenching effect for small radiation fields
G. Valdes Santurio
1
, C. E. Andersen
1
1
Technical University of Denmark, Nutech, Roskilde,
Denmark
Purpose or Objective
Fiber-coupled organic plastic scintillator detectors are
excellent for measurement of the absorbed dose to water
in small MV photon fields. This is mostly because their
small active volume and their high degree of water
equivalence result in an almost negligible perturbation of
the radiation field. However, plastic scintillators are less
ideal when we consider the signal generation and the
signal detection. For the signal generation, it is known
that the light yield per absorbed dose for electrons below
100 keV produces less light than electrons with higher
energy which is the so-called ionization density
quenching. The objective of this work was to investigate
the potential implication of this quenching effect for
output factor measurements in small 6MV photon beams.
Monte Carlo modelling was used to compute changes in
light production for different field sizes using Birks
formula applied to electrons.
Material and Methods
The quenching effect can be predicted by the Birk´s
formalism which relates the amount of light per distance
travelled by a given particle to the ionization density from
that particle as expressed by the collision stopping power
of the medium (dE/dx). This formalism introduces the
quenching parameter (
kB
), which describes that the light
produced by low energy electrons is not proportional to its
deposited energy. We implemented Birks formula in a
modified version of the application egs_chamber which is
part of the EGSnrc Monte Carlo system. The modified
application scored the light output over the absorbed dose
for each field size. This ratio will gives us how much the
quenching effect affects for that specific field size and
therefore, differences of the quenching effect when
changing the field size can be estimated. Moreover, this
ratio will give us how much the scintillator output factor
changes when the quenching effect is taken into account.
We computed light yields for square field sizes down to
0.6x0.6cm
2
with 10x10cm
2
as reference.
Results
The light output over the absorbed dose was calculated
for all field sizes. The uncertainty of all values was less
than 0.5%. Figure 1 shows the normalized scintillator light
output per dose for all field sizes and their respective
uncertainties (1 standard deviation). The straight line
represents the mean of all the obtained values and the
dashed lines represent 1% of deviation with respect to the
reference. As can be deducted from the figure, all the
ratios fell inside the range of +/- 1% of the deviation
respect the reference.
Conclusion
The study shows that for this specific value of
kB
studied
and all the limitations of the model, the quenching effect
will not significantly affect the scintillator output factor
measurements in small 6 MV photon fields, and the
quenching correction factor will be therefore close to the
unity (u=1%). The impact of the stem signal (i.e. Cerenkov
and fluorescence light produced in the optical fiber cable
during irradiations) therefore remains the main
influencing factor on such measurements.
EP-1441 Repurposing of a small clinical x-ray source
for radiobiology irradiations
M. Barry
1
, R. Jones
1
, M. Fay
1
, D. Butler
2
, J. Lehmann
1
1
Calvary Mater Newcastle, Department of Radiation
Oncology, Newcastle- NSW, Australia
2
Australian Radiation Protection and Nuclear Safety
Agency, Radiation Therapy Section, Yallambie, Australia
Purpose or Objective
Around the clock availability of irradiation capability is
desirable for creative design of radiobiology experiments.
Clinical radiation systems are often only available after
hours. Dedicated commercial cell irradiation systems are
bulky and expensive. They might not be feasible due to
financial or administrative constraints.
This work reports on the repurposing of a retired clinical
intraoperative kV irradiation system (Intrabeam™) for cell
irradiations.
Material and Methods
The Intrabeam system is designed to deliver spherical dose
distributions to surgical cavities. The in the adaption for
cell irradiations, one of the supplied applicators has been
modified to be fitted with custom collimators aiming to
deliver a homogenous field across the cell dish. Several
collimator designs have been tested and measured used
using radiochromic EBT3 film. Additionally, measurements
without a collimator were done in comparison and to
support
Monte
Carlo
simulations.
Film calibrations were performed with national standard
beams covering the energy range of the device.
The BEAMnrc code and the 'NRC swept BEAM” source
model have been used to characterize the dose
distributions and to aid collimator development.
Results
Using the film measurements, the parameters of the
Monte Carlo source model (swept angle and beam radius)
were tuned to produce the final model. Very good
agreement between measured and simulated dose profiles
for the open source at 5, 7.5 and 10 cm distance from the
tip was observed. (Figure 1)