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What is the clinical rationale?
Suit et al., IJROBP, 1988 Apr; 14(4):777-86
“
A dose distribution is superior if the
treatment volume is reduced toward the
target volume and still covers the target
volume in all dimensions.
”
The “3D” Conformal Hypothesis
By conforming the treatment more closely to the
diseased tissues, higher doses can be given without
increasing the risk of normal tissue complications.
Lichter AS. Three-dimensional conformal radiation therapy: a testable hypothesis.
Int J Radiat Oncol Biol Phys 1991;21:853-5.