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5

Radiotherapy

Planning

No adaptation

With adaptation

Castelli 2015

This is what

you

think

you get

This is what

you

get

This is what

you

can

make of it

Radiotherapy

Adaptive RT in Head and Neck

15 patients with advanced HN cancer

70 Gy 7 weeks

Weekly repeat CT

Results:

4 Gy more mean dose to the parotid than

planned without adaptation

5 Gy less mean dose to the parotid gland with

weekly replanning compared to no adaptation

Castelli 2015

Radiotherapy

Summary: ART for head and neck

Careful when adapting for tumor shrinkage

You can overcome the deleterious effect of

parotid gland shrinkage on parotid dose

One adaptation dose most of the tric

You do not need deformable registration:

if the individual plans are safe the summation

is also safe

Radiotherapy

3: Art for (Un) expected changes

Lung cancer, tumor regression (?), atelectasis

(either appearing or dissolving)

Cervix, void of hematocolpos (Uterus with

blood)

Radiotherapy

ART for (un-)expected changes

Lung cancer and atelectasis

Rianne demonstrated the traffic light warning

system (i.e. guidelines on what to do with an

image finding at the treatment machine)

Radiotherapy

New situation during treatment