1001 / 1601
6
Radiotherapy
Management system anatomical changes
“decision support system to guide the RTT in
prioritizing anatomy changes”
Radiotherapy
ART for un-expected changes
So, it is used for
safety or quality control
not for improved dose distribution perse
Radiotherapy
Adaptive RT for lung cancer
What if you would want to adapt to the shrinking
tumor?
Is it predictable?
Is replanning advisable?
Radiotherapy
Tumor reduction during RT
Zwienen et al 2008
114 patients
1 pt with progression
40% of patients noticable regression
8% >25% regression in third week
When Atelectasis present at beginning:
Atelectasis changed in 29% (23% smaller, 6%
larger)
Radiotherapy
Tumor reduction during RT
Sonke et al 2010
C/ 1vol%/day
Radiotherapy
ART for lung: mid-treatment adaptation
15 patients stage III lung cancer
Replanning after 44 of 66 Gy with new target delineation
Clinical trial