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Delineation effect on dose

Observer 1 Observer 2 Mean

IMRT

135 cm3

115 cm3

125 cm3

3D Conformal 241 cm3

195 cm3

218 cm3

Mean

188 cm3

155 cm3

Observer and technique effect on the irradiated volume

Mean Planning Target Volume: 36.3 cm3

Mean observer effect:

33 cm3

Mean technique effect:

93 cm3

•Rasch et al IJROBP 2002

Delineation effect on dose

0

10

20

30

40

50

60

0

0.5

1

1.5

2

2.5

3

3.5

4

minimum distance between the boost PTV and the chiasm (cm)

vol% receiving < 95% of the

prescribed dose

IMRT plans (

)

3D Conformal plans (

)

Dose to the target and distance from the OAR

•Rasch et al IJROBP 2002

Observer variation in the neck

18 observers

– MCA, AvL, VUMC, ARTI, RISO, MST, MCH,

UMCG, RIF, MAASTRO, UMCN, DDHK,

UMCU, Leuven, Middelheim,

1 patient

Delineation according to guidelines as

published by Gregoire et al

– R&O 2003

Prevertebral Level 1-2

Gregoire et al 2003 R&O

2 top

2 mid