744-745 / 3581
CONCLUSION : Where do we stand?
Attributes
Outcomes
Results
Technical performance
Set-up error
Can be quantified and minimized
Intra-fraction organ motion
Can be quantified. Correction is
investigational
Inter-fraction organ motion
Can be quantified and corrected
Feasibility
Patient compliance
Fair
Learning curve
Steep
Cost
Expensive
Safety
Acute AE/Toxicity
Significant reduction
Late AE/Toxicity
Data not mature
Clinical efficacy
Surrogate outcomes
-Biochemical control
No robust data yet
Adaptive> daily IGRT???
Secondary outcomes
-DFS
-QOL
Significant positive impact on
QOL
Primary outcomes
-DSS
No robust data yet