

•
NTCP models do not HAVE to be based solely on the
DVH. This has been a pragmatic approach to date
which seems to work reasonably well.
•
There are models which are true 3D spatial models,
but they are complex to apply
(Rutkowska
et al
, Phys Med Biol 2010)
•
There are metrics like the (rectal) dose-surface map
(Fiorino C
et al
, Phys Med Biol 2003, 2603-2616 )
Sanchez-Nieto B, Fenwick JF, Nahum A E
et al
2001
Biological dose surface maps: evaluation of 3D dose
data for tubular organs
Radiother. Oncol.
61
S52