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NTCP models do not HAVE to be based solely on the

DVH. This has been a pragmatic approach to date

which seems to work reasonably well.

There are models which are true 3D spatial models,

but they are complex to apply

(Rutkowska

et al

, Phys Med Biol 2010)

There are metrics like the (rectal) dose-surface map

(Fiorino C

et al

, Phys Med Biol 2003, 2603-2616 )

Sanchez-Nieto B, Fenwick JF, Nahum A E

et al

2001

Biological dose surface maps: evaluation of 3D dose

data for tubular organs

Radiother. Oncol.

61

S52