SPDS eBook March 2017

Stakeholder Panel on Dietary

Supplements: Background and

Fitness for Purpose for

SAMe

Joseph Zhou, Ph.D.

Sunshineville Health Products, Inc

AOAC Meeting Gaithersburg, Maryland

March 17, 2017

Background on SAMe

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SAMe Full Name: S-Adenosyl-L-Methionine;

Other Name: SAMe, SAM-e, or SAM;

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One of the most popular dietary supplements;

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Popular Product Format: Tablets in Blister Pack;

Dosage: 200mg-400mg/Tablet, 2-4 Tablets daily;

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Principal Structure Function:

Methyl Donor

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Medical Uses:

Depression, Osteoarthritis