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Dual Lab Validation of a Method for the Determination of Fructans in Infant 

Formula & Adult Nutritionals /        

25 Jul 2016

1

I N T R O D U C T I O N 

After opening a call for methods to determine fructans in infant formula and adult nutritionals, the 

AOAC received 4 method proposals.  So far two have been considered by the expert review panel 

(ERP), one has been rejected and the other has been accepted as first action. 

The method currently having first action status requires that a pre‐analysis is performed on the 

sample to assess the fructan type used in the product.  This information is necessary due to the use 

of fructan‐dependant correction factors. The method described in this report is designed to 

determine the fructan content without the need for correction factors thus avoiding the need for 

pre‐analysis (or knowledge of the fructan type in the product). 

The method has been developed in partnership between Nestlé Research Centre (Lausanne, 

Switzerland) and the Carbohydrate Competence Centre of Eurofins (Heerenveen, The Netherlands). 

Single lab validations have been performed in both centres, this report covers the SLV performed at 

Nestlé Research Centre. 

VALIDATION REPORT

FOR ERP USE ONLY

DO NOT DISTRIBUTE