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Dual Lab Validation of a Method for the Determination of Fructans in Infant
Formula & Adult Nutritionals /
25 Jul 2016
63
ANNEX E Experimental data accuracy study
recoveries (%)
day 1
day 6
day 10
spiked with
Oraftie P95
Nutraflora
P95
Oraftie HP
average
SD
R
average
SD
R
applied HPAEC‐PAD
ICS5000_E
ICS5000_F
ICS3000_D
recovery
recovery
sample
addition
(%)
(%)
no
level
Sample 1 Child
formula powder
low(50%)
88,5
89,3
96,4
90,8
6,3
93,2
5,6
90,9
80,8
98,7
high
(150%)
95,0
91,3
97,0
95,7
3,8
97,5
91,9
101,6
Sample 9
Toddler formula
powder milk
based
low(50%)
89,0
84,1
95,0
89,0
4,7
91,1
3,9
87,9
84,0
93,9
high
(150%)
93,3
91,3
93,6
93,2
1,2
94,9
93,4
92,9
Sample 10
Infant formula
powder milk
based
low(50%)
93,9
96,5
96,7
94,1
2,1
94,3
2,5
92,2
91,7
93,3
high
(150%)
91,3
93,5
94,7
94,6
2,9
93,1
95,3
99,9
Sample 12 Child
formula powder
low(50%)
87,3
91,3
94,0
91,0
4,9
96,2
8,0
85,4
89,2
98,9
high
(150%)
96,0
114,8
103,1
101,5
7,1
97,6
96,5
100,8
Sample 14
Infant formula
powder
FOS/GOS based
low(50%)
56,8
91,5
97,5
92,8
16,0
94,4
11,7
83,6
95,0
99,8
high
(150%)
85,4
96,9
95,1
92,2
5,5
85,7
97,7
92,5
Sample 19
Adult
nutritional RTF
high fat
low(50%)
92,2
83,6
105,7
94,8
9,2
95,0
6,9
87,7
93,9
105,7
high
(150%)
95,8
87,5
95,8
95,3
4,5
96,1
94,8
101,6
average recovery
91,3
92,3
97,7
93,7
94,1
recovery
Grubb's outlier, result rejected in the statistical
evaluation
recovery
does not meet the target range 90 ‐ 110%
recovery
meets the target range 90 ‐ 110%
VALIDATION REPORT
FOR ERP USE ONLY
DO NOT DISTRIBUTE