105 / 140
9
Discussion
How do the different agencies currently validate their sequencing
methods?
Can we validate amplicon sequencing as well as metagenomic
sequencing assays using the same set of standards? Or should
there be different standards for each?
Would the model proposed by Ladner et al. work for organisms
more complex than viruses?
• Is it just a matter of scale?
• Are there other considerations?
Development of standards for testing:
• Should they be developed internally?
• Is there a benefit to developing an overarching set of standards across
organizations and sequencing efforts? If so, what are the challenges?
What criteria/variables must be considered?
17