107 / 266
80
M
O
N
D
A
Y
1365-Pos
Board B342
A NON-CANONICAL VOLTAGE SENSOR CONTROLS GATING IN K2P K
+
CHANNELS.
Marcus Schewe
, Ehsan Nematian-Ardestani, Han Sun,
Marianne Musinszki, Sönke Cordeiro, Giovanna Bucci, Bert L. de Groot,
Stephen J. Tucker, Markus Rapedius, Thomas Baukrowitz
1366-Pos
Board B343
VARIABLE ELECTROSTATIC REPULSION MODEL OF ION-CHANNEL ACTIVA-
TION VS. GATED PORE WITH “NEUTRALIZED” S4 SEGMENTS.
H. Richard
Leuchtag
1367-Pos
Board B344
IDENTIFICATION OF RESIDUES IMPORTANT FOR THE PUFA SENSITIVITY OF
IKS.
Johan E. Larsson
, H Peter Larsson, Sara I. Liin
1368-Pos
Board B345
RELAXATION OF THE VOLTAGE SENSING MODULES OF EXCITATION-
CONTRACTION (EC) COUPLING IN MAMMALIAN SKELETAL MUSCLE.
Juan
Ferreira
, German Pequera, Carlo Manno, Eduardo Rios, Gustavo Brum
1369-Pos
Board B346
EFFECT OF 2-AMINOETHYLMETHANETHIOSULPHONATE (MTSEA) ON
THE HKV1.3_L346C AND THE HKV1.3_L346C_L418C MUTANT CHAN-
NELS.
Ann-Kathrin Diesch
, Stephan Grissmer
1370-Pos
Board B347
EDUCATION TRAVEL AWARDEE
ELUCIDATION OF MOLECULAR MECHANISM UNDERLYING KCSA’S HYS-
TERETIC GATING BEHAVIOR.
Cholpon Tilegenova
, D. Marien Cortes, Luis
G. Cuello
1371-Pos
Board B348
GINSENOSIDE RG3 ACTIVATES HUMAN EAG FAMILY OF K
+
CHANNELS
VIA ALLOSTERIC MODIFICATION OF GATING.
Wei Wu
, Alison Gardner,
Michael Sanguinetti
1372-Pos
Board B349
HERG S4-S5 ACTS AS A VOLTAGE-DEPENDENT LIGAND BINDING THE AC-
TIVATION GATE AND LOCKING IT IN A CLOSED STATE.
Olfat Malak
, Gildas
Loussouarn, Zeineb Es-Salah-Lamoureux
1373-Pos
Board B350
7-DEHYDROCHOLESTEROL MODIFIES THE OPERATION OF KV1.3 CHAN-
NELS IN T CELLS ISOLATED FROM SMITH-LEMLI-OPITZ SYNDROME
PATIENTS.
Andras Balajthy
, Zoltan Petho, Sandor Somodi, Zoltan Varga,
Maria Peter, Laszlo Vígh, Gabriella P. Szabó, Gyorgy Paragh, Gyorgy Panyi,
Peter Hajdu
1374-Pos
Board B351
KV 7.4 CHANNEL ACTIVITY IS DEPENDENT UPON PIP2 AND Gβγ SUB-
UNITS.
Oleksandr Povstyan
, Jennifer Stott, Vincenzo Barrese, Iain
Greenwood
1375-Pos
Board B352
MOUSE CARDIAC MITOBK
CA
ASSOCIATES WITH β1 SUBUNIT FAVORING
CHANNEL EXPRESSION AND ACTIVITY.
Enrique Balderas Angeles
, Ric-
cardo Olcese, Ligia Toro, Enrico Stefani
1376-Pos
Board B353
BK CHANNEL SUBPROTEOME INCLUDES NOVEL MITOCHONDRIAL PART-
NERS: ADP/ATP CARRIER AND TOM 22 IMPORT RECEPTOR.
Jin Zhang
, Zhu
Zhang, Ronghui Zhu, Min Li, Rong Lu, Yong Wu, Riccardo Olcese, Enrico
Stefani, Ligia Toro
1377-Pos
Board B354
DIFFERENTIAL EXPRESSION OF BK CHANNEL ALPHA AND BETA1 SUB-
UNITS IN RAT CEREBRAL ARTERIES.
Guruprasad Kuntamallappanavar
,
Shivantika Bisen, Anna N. Bukiya, Alex M. Dopico
1378-Pos
Board B355
BK AND CAV1.3 CHANNELS ORGANIZE IN CLUSTERS THAT CONTROL EX-
CITABILITY IN NEURONS.
Oscar Vivas
, Claudia M. Moreno, Luis F. Santana,
Bertil Hille
1379-Pos
Board B356
FUNCTIONAL IMPACT OF P320 IN HSLO1 BK CHANNEL GATING.
Guido
Gessner
, Toshinori Hoshi, Stefan H. Heinemann
1380-Pos
Board B357
BK CHANNEL C-LINKER AND AC REGION ARE CRUCIAL FOR AUXILIARY β2
SUBUNIT REGULATIONS. Zhenzhen Yan, Bin Hu, Xiying Guo, Anxi Weng,
Ling Zhong, Feng Xiao, Jiuping Ding,
Panpan Hou
1381-Pos
Board B358
EFFECTS OF SINGLE NUCLEOTIDE POLYMORPHISMS (SNPS) ON BK K
+
CHANNEL PROPERTIES.
Amber E. Plante
, Michael H. Lai, Andrea L.
Meredith
1382-Pos
Board B359
17Β-ESTRADIOL BINDS AND MODULATES BK CHANNEL THROUGH ITS Β1
AUXILIARY SUBUNIT.
Sara T. Granados
, Felipe Bravo, Romina Sepúlveda,
Danilo González-Nilo, Janneth Gonzalez, Ramón Latorre, Yolima Torres
1383-Pos
Board B360
REGULATION OF KV11.1 C-TERMINAL ISOFORM EXPRESSION BY HU PRO-
TEINS. Qiuming Gong, Matthew R. Stump,
Zhengfeng Zhou
1384-Pos
Board B361
CALCIUMMODULATES HERG FUNCTION BY ACTING AT TWO DISTINCT
BINDING SITES. Davindeep Brar, Seth Ching, Kristoffer Chin, Andrew
Nguyen,
Alan Miller
1385-Pos
Board B362
ENERGETIC CONTRIBUTIONS OF AROMATIC RESIDUES IN HV1 BLOCK BY
2-GUANIDINOIMIDAZOLES AND IN HV1 VOLTAGE-DEPENDENT ACTIVA-
TION.
Liang Hong
, Jason D. Galpin, Christopher A. Ahern, Francesco
Tombola
1386-Pos
Board B363
EXPLORATION OF THE LAST, CHANNEL OPENING TRANSITION OF THE
VOLTAGE SENSOR S4 IN A POTASSIUM CHANNEL.
Jakob Renhorn
, Luca
Conti, Fredrik Elinder
1387-Pos
Board B364
LIPOSOME-BASED IN VITRO BIOSYNTHESIS OF TWO-PORE DOMAIN PO-
TASSIUM CHANNELS FOR FUNCTIONAL STUDIES.
Marianne A. Musinszki
,
Thomas Baukrowitz
1388-Pos
Board B365
A CHARGED RESIDUE IN THE HCN CHANNEL C-LINKER STABILIZES THE
OPEN STATE.
Dana A. Page
, Edgar C. Young
1389-Pos
Board B366
CRYSTAL STRUCTURE OF THE UNLIGANDED FORM OF CYCLIC NUCLEO-
TIDE BINDING DOMAIN (CNBD) FROM HCN2 CHANNEL.
Vadim A.
Klenchin
, Claudia P. Alvarez-Baron, John Cowgill, Qiang Cui, Baron Chanda
1390-Pos
Board B367
HYDRATION OF CRITICAL RESIDUES IN THE SHAKER KV CHANNEL GOV-
ERNS THE ENERGY LANDSCAPE AND TEMPERATURE DEPENDENCE OF
CHANNEL GATING.
Sandipan Chowdhury
, Brian W. Jarecki, Baron Chanda
1391-Pos
Board B368
THE ROLE OF ION BINDING SITES IN C-TYPE INACTIVATION OF A K CHAN-
NEL. KimMatulef,
Francis Valiyaveetil
1392-Pos
Board B369
MULTI-MICROSECOND MOLECULAR DYNAMICS SIMULATIONS OF THE
HV1 PROTON CHANNEL.
Andrew Geragotelis
, Mona L. Wood, Hendrik
Goeddeke, Saleh Riahi, Scott A. Hollingsworth, J. Alfredo Freites,
Francesco Tombola, Douglas J. Tobias