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82
M
O
N
D
A
Y
1420-Pos
Board B397
FUNCTIONAL ROLES OF A CONSERVED TRYPTOPHAN AT SUBUNIT-SUB-
UNIT INTERFACES IN NMDA RECEPTOR MEMBRANE REGIONS.
Madeleine
R. Wilcox
, Nathan G. Glasgow, Jon W. Johnson
1421-Pos
Board B398
INTRA AND INTERDOMAIN MOTIONS OF THE NMDA RECEPTOR USING
SINGLE MOLECULE FRET.
Drew Dolino
, Sudeshna Chatterjee, David
Cooper, Henriette Jaurich, Swarna Ramaswamy, Soheila Rezaei Adariani,
Hugo Sanabria, Christy Landes, Vasanthi Jayaraman
1422-Pos
Board B399
MPX-004: A NEW PHARMACOLOGICAL TOOL TO STUDY THE PHYSIOLOGY
OF NMDA RECEPTORS CONTAINING THE GLUN2A SUBUNIT. Robert A.
Volkmann,
Christopher Fanger
, David R. Anderson, Frank S. Menniti
1423-Pos
Board B400
STRUCTURAL AND FUNCTIONAL COUPLING BETWEEN BK CHANNELS
AND NMDA RECEPTORS.
Jiyuan Zhang
, Qin Li, Xin Guan, Hui-Lin Pan,
Jiusheng Yan
1424-Pos
Board B401
LOCAL CA
2+
NANODOMAINS INITIATE CA
2+
/CALMODULIN-DEPENDENT
INACTIVATION OF NMDA RECEPTORS.
Gary Iacobucci
1425-Pos
Board B402
MODULATION OF GLUTAMATE RECEPTORS BY AUXILIARY PROTEINS A
STRUCTURAL INVESTIGATION.
Douglas B. Litwin
, Garam Lee, David
Maclean, Vasanthi Jayaraman
1426-Pos
Board B403
FUNCTIONAL AND STRUCTURAL CHARACTERIZATION OF THE GLUK2/
GLUK5 HETEROTETRAMER GATING MECHANISM.
Teresa Paramo
, Patricia
M.G.E. Brown, Mark R. P. Aurousseau, Maria Musgaard, Derek Bowie,
Philip C. Biggin
1427-Pos
Board B404
CONFORMATIONAL DYNAMICS OF THE GLUK2 LIGAND-BINDING DO-
MAIN.
Tyler J. Wied
, Albert Y. Lau
1428-Pos
Board B405
CID TRAVEL AWARDEE
IDENTIFICATION OF FUNCTIONAL DETERMINANTS OF KAINATE RECEP-
TOR MODULATION BY AUXILIARY PROTEIN NETO2.
Theanne N. Griffith
,
Geoffrey T. Swanson
1429-Pos
Board B406
MECHANISMS OF GLUTAMATE CAPTURE BY A CLAMSHELL BINDING DO-
MAIN.
Alvin Yu
, Héctor Salazar, Andrew J. R. Plested, Albert Y. Lau
1430-Pos
Board B407
COMPUTATIONAL STUDY OF THE IMPACT OF THE L483Y MUTATION ON
THE DESENSITIZATION OF THE AMPA RECEPTOR.
Rémi Cuchillo
, Philip C.
Biggin
1431-Pos
Board B408
STRUCTURAL EFFECTS OF PHOSPHORYLATION ON C-TERMINAL SEGMENT
OF AMPA RECEPTOR.
Caitlin E. Nurik
, Sudeshna Chattergee, Suma Devi,
David R. Cooper, Swarna S. Ramaswamy, Christy Landes, James Howe,
Vasanthi Jayaraman
1432-Pos
Board B409
ACTIVATING INDIVIDUAL SUBUNITS OF TMEM16A CALCIUM-ACTIVATED
CHLORIDE CHANNELS. Grace Jeng, Muskaan Aggarwal, Wei-Ping Yu,
Tsung-Yu Chen
1433-Pos
Board B410
MOLECULAR MECHANISMS OF PERMEATION IN TMEM16B CA
2+
-ACTIVAT-
ED CL¯ CHANNEL.
Simone Pifferi
1434-Pos
Board B411
SIZING UP THE LIPID PATHWAY IN A TMEM16 PHOSPHOLIPID SCRAMBLA-
SE.
Mattia Malvezzi
, Rabia Iqbal, Ashley Brown, Anant Menon, Alessio
Accardi
1435-Pos
Board B412
STRUCTURES OF THE MG
2+
CHANNEL CORA IN THE OPEN STATE BY CRYO
ELECTRON MICROSCOPY. Doreen Matthies, Olivier Dalmas, Mario Bor-
gnia, Pawel Dominik, Alan Merk, Prashant Rao, Bharat Reddy, Shahidul
Islam, Alberto Bartesaghi,
Eduardo Perozo
, Sriram Subramaniam
1436-Pos
Board B413
CRYSTAL STRUCTURE AND ASYMMETRIC CONFORMATION OF A K
+
CHANNEL RCK DOMAIN. Victor P. Pau, Karin Abarca-Heidemann, Eunan
Hendron, Marc Stezzi, Gino Cingolani,
Brad S. Rothberg
1437-Pos
Board B414
CONFORMATIONAL DYNAMICS OF THE CLOSED STATE OF KCSA IN LIPID
BICELLES.
Dorothy M. Kim
, Igor Dikiy, Vikrant Upadhyay, David Posson,
David Eliezer, Crina Nimigean
1438-Pos
Board B415
REGULATION OF CNGA1 CHANNEL GATING BY INTERACTIONS WITH THE
MEMBRANE.
Teresa K. Aman
, Sharona E. Gordon, William N. Zagotta
1439-Pos
Board B416
DOES BIMODAL AGONISM IN CYCLIC NUCLEOTIDE-GATED (CNG)
CHANNELS PRESERVE THE CLASSICAL BINDING SITE AND PORE STRUC-
TURE? Robynn Lester,
Edgar C. Young
Cardiac Muscle Mechanics and Structure I
(Boards B417 - B444)
1440-Pos
Board B417
DEVELOPMENT OF HIGH AFFINITY ANTI-S2 PEPTIDES FOR STABILIZING
THE MYOSIN COILED COIL. Negar Aboonasrshiraz, Ashley Huang, Cynthia
Y. Ma,
Douglas D. Root
1441-Pos
Board B418
COMPETITIVE BINDING TO MYOSIN S2 BY C-PROTEIN, ANTI-S2 PEPTIDES,
AND ANTIBODIES MODULATE MYOSIN COILED COIL STABILITY AND
MYOFIBRIL CONTRACTILITY.
Rohit Singh
, Veronica J. Zheng, Cynthia Y. Ma,
Douglas D. Root
1442-Pos
Board B419
THE N-TERMINAL DOMAINS OF MYBPC3 RESTRICT ACTIN DYNAMICS
AND INCREASE RESILIENCE IN A PHOSPHORYLATION-DEPENDENT MAN-
NER. Brett A. Colson,
Alfred Gallegos
, Brian Lin, Sakthivel Sadayappan,
David D. Thomas
1443-Pos
Board B420
PHOSPHORYLATION AND CALCIUM ANTAGONISTICALLY TUNE MYOSIN-
BINDING PROTEIN C’S MOLECULAR STRUCTURE AND FUNCTION.
Michael
J. Previs
, Ji Young Mun, Arthur J. Michalek, Samantha Beck Previs, James
Gulick, Jeffrey Robbins, David M. Warshaw, Roger Craig
1444-Pos
Board B421
STRUCTURAL MEASUREMENTS WITHIN THE M-DOMAIN REVEAL UNIQUE
DETAILS OF CARDIAC MYOSIN BINDING PROTEIN-C PHOSPHORYLA-
TION.
Brett A. Colson
, L. Michel Espinoza-Fonseca, David D. Thomas
1445-Pos
Board B422
REGULATION OF THE SUPER-RELAXED STATE OF MYOSIN BY CARDIAC
MYOSIN BINDING PROTEIN-C.
James W. McNamara
, Amy Li, Sean Lal,
Johan M. Bos, Michael J. Ackerman, Cristobal G. dos Remedios, Samantha
P. Harris, Roger Cooke