145 / 266
118
T
U
E
S
D
A
Y
2154-Pos
Board B298
A SYSTEMATIZED APPROACH TO INVESTIGATE CA
2+
SYNCHRONIZATION
IN IPSC-DERIVED CARDIOMYOCYTE NETWORKS. Aled R. Jones, David H.
Edwards, Michael J. Cummins, Alan J. Williams,
Christopher H. George
2155-Pos
Board B299
NUCLEATION OF CALCIUMWAVES IN CARDIAC CELLS: THE ROLE OF
NETWORK CONNECTIVITY.
Gonzalo Hernandez-Hernandez
, Yohannes
Shiferaw, Enric Alvarez-Lacalle
2156-Pos
Board B300
CATECHOLAMINERGIC STIMULATION OF NEURONAL NA
+
CHAN-
NELS ACCOUNTS FOR TRIGGERED ARRHYTHMIA MECHANISM IN
CPVT.
Przemysław B. Radwański
, Hsiang-Ting Ho, Bin Liu, Andriy
Belevych, Antonis Armoundas, Wolfgang Dillmann, Bjorn Knollmann,
Peter Mohler, Thomas Hund, Sándor Györke
2157-Pos
Board B301
EFFECTS OF BETA-ADRENERGIC STIMULATION ON RAT FAILING CARDIO-
MYOCYTES.
Claudia Crocini
, Raffaele Coppini, Cecilia Ferrantini, Ping Yan,
Leslie M. Loew, Elisabetta Cerbai, Corrado Poggesi, Francesco S. Pavone,
Leonardo Sacconi
2158-Pos
Board B302
CONDITIONS THAT PROMOTE GOLGI CA
2+
RELEASE FACILITATE TRAFFICK-
ING OF VEGFR-1 TO THE SURFACE MEMBRANE IN RAT VENTRICULAR
MYOCYTES.
Hannah M. Kirton
, Zhaokang Yang, Derek S. Steele
2159-Pos
Board B303
PROPENSITY AND SEVERITY OF CARDIAC ALTERNANS IS ENHANCED IN
HEART FAILURE.
Giedrius Kanaporis
, Lothar A. Blatter
2160-Pos
Board B304
NOVEL CALMODULIN MUTATION (CALM3-A103V) ASSOCIATED WITH
CPVT SYNDROME ACTIVATES ARRHYTHMOGENIC CA WAVES AND
SPARKS.
Nieves Gomez-Hurtado
, Dmytro O. Kryshtal, Christopher N.
Johnson, Walter J. Chazin, Nicole J. Boczek, Melissa L. Will, David J. Tester,
Michael J. Ackerman, Bjorn C. Knollmann
Voltage-gated Na Channels II
(Boards B305 - B314)
2161-Pos
Board B305
EDUCATION TRAVEL AWARDEE
POINT-MUTATIONS IN SKELETAL MUSCLE VOLTAGE-GATED SODIUM
CHANNELS CONFER RESISTANCE TO TETRODOTOXIN: BUT AT A
COST?
Robert E. del Carlo
, Normand Leblanc, Edmund D. Brodie, Jr., Chis
R. Feldman
2162-Pos
Board B306
INHIBITION OF A VOLTAGE-GATED SODIUM CHANNEL BY PROPOFOL
INVOLVES MODULATION OF SLOW INACTIVATION.
Elaine Yang
, Vincenzo
Carnevale, Manuel Covarrubias
2163-Pos
Board B307
A MODIFIED NEURONAL CELL LINE FOR HIGH THROUGHPUT ANALYSIS
OF VOLTAGE-GATED SODIUM CHANNELS.
Carlos G. Vanoye
, Tatiana V.
Abramova, Jean-Marc L. DeKeyser, Alfred L. George
2164-Pos
Board B308
DIII OF VOLTAGE-GATED NA
+
CHANNELS INTERACTS WITH INACTIVATION
IN THE TIME DOMAIN OF INTERMEDIATE INACTIVATION.
Eric J. Hsu
,
Wandi Zhu, Zoltan Varga, Angela R. Schubert, Jonathan R. Silva
2165-Pos
Board B309
MAPPING THE NAV1.7 CHANNEL INTERACTION WITH THE CONOTOXIN
KIIIA.
Ian H. Kimball
, Phuong T. Nguyen, Jon T. Sack, Vladimir
Yarov-Yarovoy
2166-Pos
Board B310
CLASS I ANTI-ARRHYTHMICS DIFFERENTIALLY REGULATE CARDIAC
SODIUM CHANNEL VOLTAGE-SENSING DOMAINS.
Angela R. Schubert
,
Wandi Zhu, Jonathan R. Silva
2167-Pos
Board B311
BIOPHYSICAL CHARACTERIZATION OF TWO NAV1.4 MUTATIONS IDENTI-
FIED IN PATIENTS WITH COLD-INDUCED MYOTONIA AND PERIODIC
PARALYSIS. Hugo Poulin, Pascal Gosselin-Badaroudine, Karima Habbout,
Savine Vicart, Damien Syternberg, Serena Giuliano, Sophie Nicole, Said
Bendahhou,
Mohamed Chahine
2168-Pos
Board B312
MODELING ION CHANNEL KINETICS WITH PARAMETER CON-
STRAINTS.
Cynthia B. Lombardo
, Marco A. Navarro, Autoosa Salari, Lorin
S. Milescu
2169-Pos
Board B313
CID TRAVEL AWARDEE
DEFINING THE PROTEIN:PROTEIN INTERACTION INTERFACE OF
FGF14:NAV1.6 COMPLEX. Aditya K. Singh,
Syed R. Ali
, Fernanda Laezza
2170-Pos
Board B314
ACTIVATION DYNAMICS OF SODIUM ION CHANNEL.
Matthew Harrigan
,
Vijay Pande
Voltage-gated Ca Channels
(Boards B315 - B341)
2171-Pos
Board B315
SWITCHABLE CARDIAC L TYPE CA
2+
CHANNEL TRANSCRIPT BY MINER-
ALOCORTICOID PATHWAY. Thassio Mesquita, Gaelle Auguste, Jessica
Sabourin, Gema Ruiz Hurtado, Valérie Rouffiac, Florian Le-Billan, Jérôme
Fagart, Florence Lefebvre, Say Viengchareun, Eric Morel, Ana Maria
Gomez, Marc Lombès,
Jean Pierre Benitah
2172-Pos
Board B316
TOWARD A NEW THERAPEUTIC STRATEGY IN THE TREATMENT OF
TIMOTHY SYNDROME.
Ivy E. Dick
, Rosy Joshi-Mukherjee, Wanjun Yang,
Worawan B. Limpitikul, David T. Yue
2173-Pos
Board B317
FUNCTIONAL RESCUE OF CALMODULINOPATHY IPSC-DERIVED CARDIO-
MYOCYTES -- A FORAY INTO PERSONALIZED MEDICINE.
Worawan B.
Limpitikul
, Pattraranee Limphong, Ivy E. Dick, Myoung Hyun Choi,
Wanjun Yang, Jennifer Babich, David J. Tester, Michael J. Ackerman,
Gordon F. Tomaselli, David T. Yue
2174-Pos
Board B318
TOWARDS A STRUCTURAL PERSPECTIVE OF CALCIUM REGULATION OF
L-TYPE CALCIUM CHANNELS.
Rahul Banerjee
, Manu Ben-Johny, Ivy Ellen
Dick, David Tuckchow Yue
2175-Pos
Board B319
BLOCKING OF T-TYPE CALCIUM CHANNELS BY TTA-A2 REVEALS A CON-
SERVATIVE BINDING SITE FOR STATE-DEPENDENT ANTAGONISTS. Eduardo
Chavez-Colorado, Zazil Herrera-Carrillo,
Juan C. Gomora
2176-Pos
Board B320
FUNCTIONAL AND MOLECULAR INTERACTION OF PHENYLALKYLAMINES
AND DIHYDROPYRIDINES WITH THE MODEL CALCIUM CHANNEL CAV-
AB.
Tamer M. Gamal El-Din
, Teresa M. Swanson, Lin Tang, Ning Zheng,
William A. Catterall
2177-Pos
Board B321
NITRIC OXIDE INHIBITS HIGH VOLTAGE-ACTIVATED CALCIUM CHANNELS
THROUGH S-NITROSYLATION.
Menghua Zhou
, Alexis Bavencoffe, Hui-Lin
Pan