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887-Plat
9:15 am
A TRIO OF CATIONS IN GRAMICIDIN A CHANNEL: IMPORTANCE OF
QUANTUM EFFECTS TO DESCRIBE ION SELECTIVITY OF K
+
AND NA
+
, AND
PROTON TRANSFER.
Van Ngo
, Sergei Yu Noskov
888-Plat
9:30 am
REDUCING IAPP AGGREGATION WITH MITOCHONDRIAL HUMANIN
PEPTIDES; RESULTS FROM SIMULATIONS AND EXPERIMENTS.
Zachary A.
Levine
, Alan Okada, Kazuki Teranishi, Ralf Langen, Joan-Emma Shea
889-Plat
9:45 am
RATIONAL DEVELOPMENT OF A NEW TYPE OF HBV CAPSID INHIBITORS
BY A COMBINATION OF MICROSECOND-SCALE MOLECULAR DYNAMICS
AND DOCKING. Maksym Korablyov,
Anna Pavlova
, James Gumbart
890-Plat
10:00 am
HOLLIDAY JUNCTION THERMODYNAMICS AND STRUCTURE: COMPARI-
SONS OF COARSE-GRAINED SIMULATIONS AND EXPERIMENTS.
Francis
W. Starr
, Wujie Wang, Laura M. Nocka, Brianne Z. Wiemann, Daniel M.
Hinckley, Ishita Mukerji
Platform
Membrane Pumps, Transporters, and
Exchangers
8:15 am - 10:15 am, Room 515A
Co-Chairs
Merritt Maduke, Stanford University
Pernilla Wittung-Stafshede, Umeå Univeristy, Sweden
891-Plat
8:15 am
AN OUTWARD-FACING OPEN CONFORMATIONAL STATE IN A CLC TRANS-
PORTER. Sherwin J. Abraham, Tanmay Chavan, Ricky C. Cheng, Cristina
Fenollar-Ferrer, Wei Han, Shahidul M. Islam, Tao Jiang, Chandra M.
Khantwal, Irimpan I. Mathews, Richard A. Stein, Benoit Roux, Lucy R.
Forrest, Hassane S. Mchaourab, Emad Tajkhorshid,
Merritt Maduke
892-Plat
8:30 am
TRANSPORT MECHANISM OF THE EIIC GLUCOSE SUPERFAMILY OF
TRANSPORTERS.
Zhenning Ren
, Jason G. McCoy, Vitali Stanevich, Jumin
Lee, Sharmistha Mitra, Elena J. Levin, Sebastien Poget, Matthias Quick,
Wonpil Im, Ming Zhou
893-Plat
8:45 am
DIRECT VISUALIZATION OF GLUTAMATE TRANSPORTER TRANSPORT
CYCLE. Yi Ruan, Atsushi Miyagi, Xiaoyu Wang, Mohamed Chami, Henning
Stahlberg, Olga Boudker,
Simon Scheuring
894-Plat
9:00 am
RESOLVING ACTIVE ION TRANSPORT AT THE SINGLE MOLECULE LEVEL
FOR THE FIRST TIME.
Salome Veshaguri
, Sune M. Christensen, Gerdi C.
Kemmer, Mads P. Møller, Garima Ghale, Christina Lohr, Andreas L.
Christensen, Bo H. Justesen, Ida L. Jørgensen, Jürgen Schiller, Nikos S.
Hatzakis, Michael Grabe, Thomas Gunther Pomorski, Dimitrios Stamou
895-Plat
9:15 am
PROTEIN INTERACTIONS THAT ENABLE SAFE AND EFFICIENT COPPER ION
TRANSPORT IN THE HUMAN CYTOPLASM.
Pernilla Wittung-Stafshede
896-Plat
9:30 am
INTERNATIONAL TRAVEL AWARDEE
DISSECTING THE CATALYTIC CYCLE OF THE SEROTONIN TRANSPORTER.
Peter S. Hasenhuetl
, Michael Freissmuth, Harald H. Sitte, Klaus Schicker,
Yang Li, Walter Sandtner
897-Plat
9:45 am
TRANSLOCASE ACTIVITY AND ASYMMETRIC MODEL MEMBRANES
PROBED BY NEUTRON SCATTERING.
Allison M. Whited
, Frederick A.
Heberle, Robert F. Standaert, Jonathan David Nickels, Xiaolin Cheng, John
Katsaras, Alexander Johs
898-Plat
10:00 am
FUNCTIONAL CHARACTERIZATION OF CALCIUM-ACTIVATED PHOSPHO-
LIPID SCRAMBLASE ACTIVITY OF NHTMEM16.
Tao Jiang
, Sundar
Thangapandian, Emad Tajkhorshid
Platform
Protein Stability, Folding, and Chaperones I
8:15 am - 10:15 am, Room 515B
Co-Chairs
Susan Marqusee, University of California, Berkeley
Hugo Sanabria, Clemson University
899-Plat
8:15 am
MECHANICAL UNFOLDING OF E. COLI RNASE H REVEALS AN INTERME-
DIATE WITH A FORCE-INDUCED SHIFT IN THE RATE-LIMITING BARRIER.
Diane M. Wiener
, Jesse W. Dill, Susan Marqusee
900-Plat
8:30 am
IN-CELL PROTEIN FOLDING - PAPS SYNTHASES. Oliver Brylski, David
Gnutt,
Simon Ebbinghaus
901-Plat
8:45 am
PROVING THE ROLE OF ENTROPIC ELASTICITY IN PROTEIN FOLDING.
Jessica Valle-Orero
, Edward C. Eckels, Ionel Popa, Jaime Andres
Rivas-Pardo, Julio M. Fernandez
902-Plat
9:00 am
SUB-MILLISECOND UNFOLDING KINETIC SPECTRA REVEALS INTERMEDI-
ATE TRANSITIONS.
Hugo Sanabria
, Katherina Hemmen, Dmitro Rodnin,
Daniel Rohrbeck, Soheila Rezai Adariani, Ralf Kühnemuth, Claus A. M.
Seidel
903-Plat
9:15 am
STUDYING THE FUNCTION OF BAP IN THE NUCLEOTIDE CYCLE OF BIP BY
SPFRET USING MFD-PIE.
Daniela Wengler
, Mathias Rosam, Jelle Hendrix,
Johannes Buchner, Don C. Lamb
904-Plat
9:30 am
THE EFFECT OF LOOP INSERTIONS ON THE FOLDING OF TANDEM-REPEAT
PROTEINS.
Albert Perez-Riba
, Ewan R. Main, Laura S. Itzhaki
905-Plat
9:45 am
LINKING MECHANOCHEMISTRY TO PROTEIN FOLDING AT THE SINGLE
BOND LEVEL.
Amy EM Beedle
, Sergi Garcia-Manyes
906-Plat
10:00 am
FOLDING DYNAMICS OF B1 DOMAIN OF PROTEIN G USING SINGLE MOL-
ECULE FORCE SPECTROSCOPY.
Dena Izadi
Platform
Excitation-Contraction Coupling
8:15 am - 10:15 am, Room 501ABC
Co-Chairs
Bradley Launikonis, University of Queensland, Australia
Isabelle Marty, Grenoble Institut des Neurosciences, France
907-Plat
8:15 am
THE MICROTUBULE-ASSOCIATED PROTEIN CLIMP-63 IS A NEWMEMBER
OF THE CALCIUM RELEASE COMPLEX. Alexis Osseni, Muriel Sebastien,
Julien Fauré, Anne Fourest-Lieuvin,
Isabelle Marty
908-Plat
8:30 am
STRUCTURAL INSIGHTS INTO RYANODINE RECEPTOR-FKBP12 INTERAC-
TIONS IN WILD-TYPE AND MUTATED STATES.
Zhiguang Yuchi
, Siobhan
MWong King Yuen, Kelvin Lau, Ainsley Underhill, Razvan Cornea, James
Fessenden, Filip Van Petegem