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909-Plat
8:45 am
CALSEQUESTRIN DEPOLYMERIZES WHEN CA
2+
CONCENTRATION DECAYS
IN THE SARCOPLASMIC RETICULUM OF SKELETAL MUSCLE.
Carlo Manno
,
Lourdes Figueroa, Dirk Gillespie, Eduardo Rios
910-Plat
9:00 am
SHEET-LIKE REMODELING OF THE T-SYSTEM OF VENTRICULAR CARDIO-
MYOCYTES IN HEART FAILURE.
Thomas Seidel
, Martin Tristani-Firouzi,
Craig H. Selzman, Frank B. Sachse
911-Plat
9:15 am
DIFFUSION PROPERTIES OF CARDIAC T-TUBULAR SYSTEM. Marina
Scardigli,
Claudia Crocini
, Cecilia Ferrantini, Raffaele Coppini, Chiara Tesi,
Elisabetta Cerbai, Corrado Poggesi, Francesco S. Pavone, Leonardo
Sacconi
912-Plat
9:30 am
MICROTUBULE-DEPENDENT ALTERATIONS TO MECHANICAL PROPERTIES
AND MECHANOTRANSDUCTION IN SKELETAL MUSCLE.
Jaclyn P. Kerr
,
Guoli Shi, W Jonathan Lederer, Kelley M. Virgilio, Sylvia S. Blemker, Stuart
S. Martin, Roberto Raiteri, Christopher W. Ward
913-Plat
9:45 am
CALCIUM ENTRY UNITS: EXERCISE-DEPENDENT FORMATION OF NEW
SR-TT JUNCTIONS CONTAINING STIM1 AND ORAI1 IN MUSCLE. Simona
Boncompagni, Antonio Michelucci, Laura Pietrangelo, Robert T. Dirksen,
Feliciano Protasi
914-Plat
10:00 am
RYANODINE RECEPTOR ACTIVITY REGULATES THE LEVELS OF CA
2+
EXTRU-
SION AND STORE-OPERATED CA
2+
ENTRY IN SKELETAL MUSCLE. Tanya R.
Cully, Rocky H. Choi, Thomas R. Shannon,
Bradley S. Launikonis
Platform
DNA Structure and Dynamics
8:15 am - 10:15 am, Room 511ABC
Co-Chairs
Vincent Croquette, LPS-ENS Research University, France
Catherine Tardin, Institute of Pharmacology and Structural Biology, France
915-Plat
8:15 am
REVISITING SEQUENCING BY HYBRIDIZATION AT THE SINGLE MOLECULE
LEVEL USING THE UNZIPPING ASSAY.
Vincent Croquette
, Saurabh Raj,
Jean-François Allemand, David Bensimon, Jean-Baptiste Boulé
916-Plat
8:30 am
MODELING SECONDARY STRUCTURAL ELEMENTS IN PROGRAMMED DNA
ASSEMBLIES.
Keyao Pan
, Mark Bathe
917-Plat
8:45 am
THE OVERSTRETCHING TRANSITION OF DIAMINOPURINE SUBSTITUTED
TRIPLY HYDROGEN-BONDED DNA.
Daniel T. Kovari
, Matteo Cristofalo,
David Dunlap, Laura Finzi
918-Plat
9:00 am
THREE DIMENSIONAL DYNAMICS AND FLUCTUATIONS OF DNA-NANO-
GOLD DIMERS BY INDIVIDUAL-PARTICLE ELECTRON TOMOGRAPHY.
Lei
Zhang
, Dongsheng Lei, Jessica M. Smith, Huimin Tong, Xing Zhang, Paul
Alivisatos, Gang Ren
919-Plat
9:15 am
BRANCHPOINT STRUCTURE OF DNA THREEWAY JUNCTIONS. Anita
Toulmin,
Michael J. Morten
, Tara Sabir, Laura E. Baltierra-Jasso, Peter
McGlynn, Gunnar F. Schröder, Brian Smith, Steven W. Magennis
920-Plat
9:30 am
DYNAMICS OF HUMAN TELOMERIC G-QUADRUPLEX PROBED BY SINGLE
MOLECULE FLUORESCENCE-FORCE SPECTROSCOPY.
Jaba Mitra
, Thuy
T.M. Ngo, Taekjip Ha
921-Plat
9:45 am
PROBING A LABEL-FREE LOCAL BEND IN DNA BY SINGLE MOLECULE
TETHERED PARTICLE MOTION. Annaël Brunet, Sébastien Chevalier,
Nicolas Destainville, Manoel Manghi, Philippe Rousseau, Maya Sahi,
Laurence Salome,
Catherine Tardin
922-Plat
10:00 am
QUANTIFYING THE ION ATMOSPHERE OF UNFOLDED, SINGLE-STRANDED
NUCLEIC ACIDS.
David R. Jacobson
, Omar A. Saleh
CPOW Committee Meeting
8:30 am - 10:30 am, Room 408A
Exhibitor Presentation
Sophion together with Biolin Scientific
9:30 am - 11:00 am, Room 505
Pioneering Ion Channels - Expanding the Boundaries of Automated
Patch Clamp
Recent advances in automated patch clamp for voltage and ligand gated
ion channels with emphasis on NMDA, cardiac safety and induced plu-
ripotent stem cells
Speakers
Timm Danker, NMI, Germany
Automated Patch Clamp on Crdiac Ion Channels and Multiwell MEA
Recordings on Human iPSC-derived Cardiomyocytes: a Complementary
Approach for Predictable Proarhytmia Assessments
Caterina Virginio, Aptuit
NMDA Receptors: Meaningful Biophysical and Pharmacological Studies
to Redefine Ligands Properties
Denise Franz, University of Rostock, Germany
Electrophysiological Characterization of Human Induced Ppluripotent
Stem Cell-derived Dopaminergic Neurons on the QPatch
Career Center Workshop
Ten Tough Industrial Interview Questions
(and Ten Pretty Good Responses)
10:00 am - 11:00 am, Room 518
You’ve been invited to interview with that drug development company
that you’ve always wanted to work for. You’ve soaked up the details of
the position description. You are confident in your ability to do the job, as
well as answer any/all technical questions during the interview process.
The day is yours…until…that first question catches you by surprise and
your confidence begins to wilt. Be prepared for those non-technical ques-
tions that you will almost certainly hear at some point, know why they
are asked, and learn what a good (if not great) response to each question
might be by attending this workshop.
Exhibits
10:00 am - 5:00 pm, West Hall
Coffee Break
10:15 am - 11:00 am, West Hall